Physicians, policymakers, and researchers are increasingly focused on finding ways to
decrease opioid use and overdose in the United States both of which have sharply …

Importance Uncontrolled and indiscriminate prescribing of opioids has led to an opioid crisis
that started in North America and spread throughout high-income countries. The aim of this …

Importance Opioids administered to treat postsurgical pain are a major contributor to the
opioid crisis, leading to chronic use in a considerable proportion of patients. Initiatives …

Persistent postoperative opioid use is thought to contribute to the ongoing opioid epidemic
in the United States. However, efforts to study and address the issue have been stymied by …

Post-surgical opioid prescribing intended for the short-term management of acute pain may
lead to long-term opioid use. This study was undertaken to determine the prevalence of …

BACKGROUND: Determinants of the duration of opioid use after surgery have not been
reported. We hypothesized that both preoperative psychological distress and substance …

In the midst of an epidemic of opioid abuse and overdose-related morbidity and mortality,
the use of opioids remains the most common means of providing analgesia in the …

Background While persistent opioid use after surgery has been the subject of a large
number of studies, it is unknown how much variability in the definition of persistent use …

Background The prevalence of licit and illicit opioid use is growing, and a greater
percentage of chronically opioid-consuming patients are presenting for surgery. These …

Objective: Evaluate the association between postoperative opioid prescribing and new
persistent opioid use. Summary Background Data: Opioid-nave patients who develop new …