Functional connectivity in antipsychotic-treated and antipsychotic-naive patients with first-episode psychosis and low risk of self-harm or aggression: a secondary …

S Chopra, SM Francey, B O'Donoghue… - JAMA …, 2021 - jamanetwork.com
Importance Altered functional connectivity (FC) is a common finding in resting-state
functional magnetic resonance imaging (rs-fMRI) studies of people with psychosis, yet how …

Network-level dysconnectivity in drug-naïve first-episode psychosis: dissociating transdiagnostic and diagnosis-specific alterations

Q Gong, X Hu, W Pettersson-Yeo, X Xu, S Lui… - …, 2017 - nature.com
The neuroimaging literature provides compelling evidence for functional dysconnectivity in
people with psychosis. However, it is likely that at least some of the observed alterations …

Brain connectivity abnormalities predating the onset of psychosis: correlation with the effect of medication

A Schmidt, R Smieskova, J Aston, A Simon… - JAMA …, 2013 - jamanetwork.com
Importance Brain imaging studies have identified robust changes in brain structure and
function during the development of psychosis, but the contribution of abnormal brain …

Baseline striatal functional connectivity as a predictor of response to antipsychotic drug treatment

DK Sarpal, M Argyelan, DG Robinson… - American Journal of …, 2016 - Am Psychiatric Assoc
Objective: Clinical response to antipsychotic drug treatment is highly variable, yet prognostic
biomarkers are lacking. The authors recently demonstrated that successful antipsychotic …

Abnormal long-and short-range functional connectivity in adolescent-onset schizophrenia patients: a resting-state fMRI study

S Wang, Y Zhan, Y Zhang, L Lyu, H Lyu, G Wang… - Progress in Neuro …, 2018 - Elsevier
Background Human brain is a topologically complex network embedded in anatomical
space, and anatomical distance may affect functional connectivity (FC) in schizophrenia …

Duration of untreated psychosis correlates with brain connectivity and morphology in medication-naive patients with first-episode psychosis

JO Maximo, EA Nelson, WP Armstrong… - Biological Psychiatry …, 2020 - Elsevier
Abstract Background In the United States, the average duration of untreated psychosis
(DUP) is 21 months, and it remains unknown how longer DUP may affect brain functioning in …

Functional connectivity in distinct cognitive subtypes in psychosis

KE Lewandowski, JM McCarthy, D Öngür… - Schizophrenia …, 2019 - Elsevier
Background Cognitive dysfunction is common in psychotic disorders, and may reflect
underlying pathophysiology. However, substantial cognitive heterogeneity exists both within …

Increased short-range and long-range functional connectivity in first-episode, medication-naive schizophrenia at rest

W Guo, F Liu, C Xiao, J Liu, M Yu, Z Zhang… - Schizophrenia …, 2015 - Elsevier
Objective Schizophrenia is conceived as a disconnection syndrome and anatomical
distance may affect functional connectivity (FC) in schizophrenia patients. However, whether …

Disrupted resting-state functional connectivity in minimally treated chronic schizophrenia

X Wang, M Xia, Y Lai, Z Dai, Q Cao, Z Cheng… - Schizophrenia …, 2014 - Elsevier
Objective The pathophysiology of chronic schizophrenia may reflect long term brain
changes related to the disorder. The effect of chronicity on intrinsic functional connectivity …

Dynamic functional connectivity impairments in early schizophrenia and clinical high-risk for psychosis

Y Du, SL Fryer, Z Fu, D Lin, J Sui, J Chen, E Damaraju… - Neuroimage, 2018 - Elsevier
Individuals at clinical high-risk (CHR) for psychosis are characterized by attenuated
psychotic symptoms. Only a minority of CHR individuals convert to full-blown psychosis …