Silica is utilized extensively in industrial and commercial applications as a chemical raw
material, increasing its exposure and hazardous potential to populations, with silicosis …

Macrophage pyroptosis has recently been involved in some inflammatory and fibrosis
diseases, however, the role of macrophage pyroptosis in silica-induced pulmonary fibrosis …

Crystalline silica (CS) particles are ubiquitous in the environment, especially in occupational
conditions, and exposure to respirable CS causes silicosis. The initial response to CS is …

Silicosis is a diffuse fibrotic lung disease in which excessive inflammatory responses are
triggered by silica exposure. Pyroptosis, a pro-inflammatory mode of programmed cell death …

Silicosis is a long‐established public health issue in developing countries due to
increasingly serious air pollution and poorly implemented occupational safety regulation …

Environmental exposure to crystalline silica (CS) can lead to silicosis. Alveolar
macrophages (AMs) play a crucial role in the pathogenesis of silicosis. Previously, we …

Silicosis is a type of pneumoconiosis caused by the inhalation of silica dust. It is
characterized by inflammation and fibrosis of the lung. Although many studies have reported …

Silica is an essential substrate of various materials, and inhaling silica induces pulmonary
diseases potentially associated with macrophage pyroptosis. Utilizing silica of micro-and …

Exposure to crystalline silica (CS) particles in worksites and dwellings can lead to silicosis
due to excessive fibroblast activation. Considering their immuno-regulatory activities, the …

Long-term exposure to crystalline silica particles leads to silicosis characterized by
persistent inflammation and progressive fibrosis in the lung. So far, there is no specific …