DNA structure and function
A Travers, G Muskhelishvili - The FEBS journal, 2015 - Wiley Online Library
The proposal of a double‐helical structure for DNA over 60 years ago provided an eminently
satisfying explanation for the heritability of genetic information. But why is DNA, and not …
satisfying explanation for the heritability of genetic information. But why is DNA, and not …
[PDF][PDF] Supercoil-driven DNA structures regulate genetic transactions
F Kouzine, D Levens - Front Biosci, 2007 - academia.edu
The structural diversity of DNA 3. What forces promote structural isomerizations? 4.
Restrained vs. unrestrained supercoils 5. Supercoiling forces regulate prokaryotic genes 6 …
Restrained vs. unrestrained supercoils 5. Supercoiling forces regulate prokaryotic genes 6 …
[引用][C] Why bend DNA?
AA Travers - Cell, 1990 - Elsevier
The distortion of DNA from the straight, regular-and essentially mythical-double-helical
structure beloved of textbooks is a ubiquitous feature of DNA-protein complexes. A common …
structure beloved of textbooks is a ubiquitous feature of DNA-protein complexes. A common …
B-DNA twisting correlates with base-pair morphology
AA Gorin, VB Zhurkin, K Wilma - Journal of molecular biology, 1995 - Elsevier
The observed sequence dependence of the mean twist angles in 38B-DNA crystal structures
can be understood in terms of simple geometrical features of the constituent base-pairs …
can be understood in terms of simple geometrical features of the constituent base-pairs …
Roles of supercoiled DNA structure in DNA transactions
R Kanaar, NR Cozzarelli - Current Opinion in Structural Biology, 1992 - Elsevier
The structure of supercoiled DNA has recently been ascertained using experimental and
computational methods. Negative supercoiling restricts the ensemble of DNA conformations …
computational methods. Negative supercoiling restricts the ensemble of DNA conformations …
The functional response of upstream DNA to dynamic supercoiling in vivo
F Kouzine, S Sanford, Z Elisha-Feil… - Nature structural & …, 2008 - nature.com
Because RNA polymerase is a powerful motor, transmission of transcription-generated
forces might directly alter DNA structure, chromatin or gene activity in mammalian cells. Here …
forces might directly alter DNA structure, chromatin or gene activity in mammalian cells. Here …
DNA curvature and flexibility in vitro and in vivo
JP Peters, LJ Maher - Quarterly reviews of biophysics, 2010 - cambridge.org
It has been more than 50 years since the elucidation of the structure of double-helical DNA.
Despite active research and progress in DNA biology and biochemistry, much remains to be …
Despite active research and progress in DNA biology and biochemistry, much remains to be …
The importance of being supercoiled: how DNA mechanics regulate dynamic processes
L Baranello, D Levens, A Gupta, F Kouzine - Biochimica et Biophysica Acta …, 2012 - Elsevier
Through dynamic changes in structure resulting from DNA–protein interactions and
constraints given by the structural features of the double helix, chromatin accommodates …
constraints given by the structural features of the double helix, chromatin accommodates …
[HTML][HTML] Spontaneous sharp bending of double-stranded DNA
TE Cloutier, J Widom - Molecular cell, 2004 - cell.com
Sharply bent DNA is essential for gene regulation in prokaryotes and is a major feature of
eukaryotic nucleosomes and viruses. The explanation normally given for these phenomena …
eukaryotic nucleosomes and viruses. The explanation normally given for these phenomena …
Stereochemical basis of DNA bending by transcription factors
M Suzuki, N Yagi - Nucleic acids research, 1995 - academic.oup.com
Superstructure-formation of DNA plays an Important role In transcription regulation as well
as In chromatln formation. To understand the stereochemical basis of DNA bending by …
as In chromatln formation. To understand the stereochemical basis of DNA bending by …