The proposal of a double‐helical structure for DNA over 60 years ago provided an eminently
satisfying explanation for the heritability of genetic information. But why is DNA, and not …

The structural diversity of DNA 3. What forces promote structural isomerizations? 4.
Restrained vs. unrestrained supercoils 5. Supercoiling forces regulate prokaryotic genes 6 …

The distortion of DNA from the straight, regular-and essentially mythical-double-helical
structure beloved of textbooks is a ubiquitous feature of DNA-protein complexes. A common …

The observed sequence dependence of the mean twist angles in 38B-DNA crystal structures
can be understood in terms of simple geometrical features of the constituent base-pairs …

The structure of supercoiled DNA has recently been ascertained using experimental and
computational methods. Negative supercoiling restricts the ensemble of DNA conformations …

Because RNA polymerase is a powerful motor, transmission of transcription-generated
forces might directly alter DNA structure, chromatin or gene activity in mammalian cells. Here …

It has been more than 50 years since the elucidation of the structure of double-helical DNA.
Despite active research and progress in DNA biology and biochemistry, much remains to be …

Through dynamic changes in structure resulting from DNA–protein interactions and
constraints given by the structural features of the double helix, chromatin accommodates …

Sharply bent DNA is essential for gene regulation in prokaryotes and is a major feature of
eukaryotic nucleosomes and viruses. The explanation normally given for these phenomena …

Superstructure-formation of DNA plays an Important role In transcription regulation as well
as In chromatln formation. To understand the stereochemical basis of DNA bending by …