Regulation of milk protein gene expression

JM Rosen, SL Wyszomierski… - Annual review of …, 1999 - annualreviews.org
▪ Abstract Studies using both transgenic mice and transfected mammary epithelial cells have
established that composite response elements containing multiple binding sites for several …

Composite response elements mediate hormonal and developmental regulation of milk protein gene expression.

JM Rosen, C Zahnow, A Kazansky… - Biochemical Society …, 1998 - europepmc.org
Our laboratory has been studying the mechanisms by which hormones regulate the
expression of differentiated function in the normal mammary gland and how these regulatory …

Multihormonal regulation of milk protein gene expression.

JM Rosen, JR Rodgers, CH Couch, CA Bisbee… - 1986 - cabidigitallibrary.org
Milk protein gene expression in mammary epithelial cells is regulated by interactions of
many peptide and steroid hormones both at the transcriptional and post-transcriptional level …

Glucocorticoid regulation of rat whey acidic protein gene expression involves hormone-induced alterations of chromatin structure in the distal promoter region.

S Li, JM Rosen - Molecular Endocrinology, 1994 - academic.oup.com
Milk protein gene expression is regulated by the synergistic interactions of several
lactogenic hormones, including insulin, PRL, and glucocorticoids. Whey acidic protein …

Glucocorticoid receptor binding sites in the promoter region of milk protein genes

T Welte, S Philipp, C Cairns, JÅ Gustafsson… - The Journal of Steroid …, 1993 - Elsevier
The action of glucocorticoids on the induction of the two milk protein genes β-casein and
whey acidic protein (WAP) is delayed and appears to be indirect. The response requires a …

Developmental and environmental regulation of a mammary gland-specific nuclear factor essential for transcription of the gene encoding beta-casein.

M Schmitt-Ney, B Happ, RK Ball… - Proceedings of the …, 1992 - National Acad Sciences
During the lactation period, mammary epithelial cells secrete large amounts of milk proteins.
The coordinate regulation of milk protein expression is effected by the lactogenic hormones …

Hormonal regulation of milk protein gene expression.

BK Vonderhaar, SE Ziska - 1989 - cabidigitallibrary.org
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β-casein gene promoter activity is regulated by the hormone-mediated relief of transcriptional repression and a mammarygland-specific nuclear factor

M Schmitt-Ney, W Doppler, RK Ball… - Molecular and cellular …, 1991 - Taylor & Francis
Transcription from the β-casein milk protein gene promoter is induced by the synergistic
action of glucocorticoid and prolactin hormones in the murine mammary epithelial cell line …

The nuclear factor YY1 participates in repression of the beta-casein gene promoter in mammary epithelial cells and is counteracted by mammary gland factor during …

VS Meier, B Groner - Molecular and cellular biology, 1994 - Taylor & Francis
Expression of the beta-casein milk protein gene in the mammary epithelial cell line HC11 is
primarily regulated at the transcriptional level. A 338-bp segment of promoter sequence 5 …

Interaction of DNA-binding proteins with a milk protein gene promoter in vitro: identification of a mammary gland-specific factor

CJ Waston, KE Gordon, M Robertson… - Nucleic acids …, 1991 - academic.oup.com
The minimal 5′ regulatory region of the sheep β-lactoglobulin gene (BLG), as defined in
transgenic mice, was used to identify nuclear factors which may be involved in milk protein …