Hemorrhagic transformation after ischemic stroke: mechanisms and management

JM Hong, DS Kim, M Kim - Frontiers in Neurology, 2021 - frontiersin.org
Symptomatic hemorrhagic transformation (HT) is one of the complications most likely to lead
to death in patients with acute ischemic stroke. HT after acute ischemic stroke is diagnosed …

[HTML][HTML] Hemorrhagic transformation after cerebral infarction: current concepts and challenges

J Zhang, Y Yang, H Sun, Y Xing - Annals of translational medicine, 2014 - ncbi.nlm.nih.gov
Hemorrhagic transformation (HT) is a frequent complication of acute ischemic stroke that is
especially common after thrombolytic therapy. The risk of HT limits the applicability of tissue …

Hemorrhagic transformation in ischemic stroke and the role of inflammation

E Spronk, G Sykes, S Falcione, D Munsterman… - Frontiers in …, 2021 - frontiersin.org
Hemorrhagic transformation (HT) is a common complication in patients with acute ischemic
stroke. It occurs when peripheral blood extravasates across a disrupted blood brain barrier …

Hemorrhagic transformation after tissue plasminogen activator reperfusion therapy for ischemic stroke: mechanisms, models, and biomarkers

W Wang, M Li, Q Chen, J Wang - Molecular neurobiology, 2015 - Springer
Intracerebral hemorrhagic transformation (HT) is well recognized as a common cause of
hemorrhage in patients with ischemic stroke. HT after acute ischemic stroke contributes to …

Blood–brain barrier disruption and hemorrhagic transformation in acute ischemic stroke: systematic review and meta-analysis

F Arba, C Rinaldi, D Caimano, F Vit, G Busto… - Frontiers in …, 2021 - frontiersin.org
Introduction: Hemorrhagic transformation (HT) is a complication of reperfusion therapy for
acute ischemic stroke. Blood–brain barrier (BBB) disruption is a crucial step toward HT; …

Predictors and early outcome of hemorrhagic transformation after acute ischemic stroke

M Kablau, SH Kreisel, T Sauer, J Binder… - Cerebrovascular …, 2011 - karger.com
Background: Hemorrhagic transformation (HT) after acute ischemic stroke is frequently
detected using magnetic resonance imaging (MRI), in particular in patients treated with …

Intracranial hemorrhage associated with revascularization therapies

P Khatri, LR Wechsler, JP Broderick - Stroke, 2007 - Am Heart Assoc
Background and Purpose—This review discusses the state of our current knowledge on
hemorrhagic transformation (HT) and summarizes key factors to be considered when …

Hemorrhagic transformation: a review of the rate of hemorrhage in the major clinical trials of acute ischemic stroke

ES Sussman, ES Connolly Jr - Frontiers in neurology, 2013 - frontiersin.org
Acute ischemic stroke is a devastating disease that is often complicated by hemorrhagic
transformation. While significant advances have been made over the past two decades with …

Triggers and mediators of hemorrhagic transformation in cerebral ischemia

X Wang, EH Lo - Molecular neurobiology, 2003 - Springer
Intracerebral hemorrhagic transformation is a multifactorial phenomenon in which ischemic
brain tissue converts into a hemorrhagic lesion with blood-vessel leakage, extravasation …

Hemorrhagic transformation after ischemic stroke in animals and humans

GC Jickling, DZ Liu, B Stamova… - Journal of Cerebral …, 2014 - journals.sagepub.com
Hemorrhagic transformation (HT) is a common complication of ischemic stroke that is
exacerbated by thrombolytic therapy. Methods to better prevent, predict, and treat HT are …