Antidiabetic therapies and Alzheimer disease
BB Bendlin - Dialogues in clinical neuroscience, 2019 - Taylor & Francis
Given current lack of therapies for dementia, there is substantial interest in identifying
potentially modifiable risk factors. Clarifying the potential of these factors to mitigate risk as …
potentially modifiable risk factors. Clarifying the potential of these factors to mitigate risk as …
Diabetes: Risk factor and translational therapeutic implications for Alzheimer's disease
J Cummings, A Ortiz, J Castellino… - European Journal of …, 2022 - Wiley Online Library
Type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) commonly co‐occur. T2DM
increases the risk for AD by approximately twofold. Animal models provide one means of …
increases the risk for AD by approximately twofold. Animal models provide one means of …
Crosstalk between Alzheimer's disease and diabetes: a focus on anti-diabetic drugs
Alzheimer's disease (AD) and Type 2 diabetes mellitus (T2DM) are two of the most common
age-related diseases. There is accumulating evidence of an overlap in the …
age-related diseases. There is accumulating evidence of an overlap in the …
[HTML][HTML] New views and possibilities of antidiabetic drugs in treating and/or preventing mild cognitive impairment and Alzheimer's Disease
KL Zhong, F Chen, H Hong, X Ke, YG Lv, SS Tang… - Metabolic Brain …, 2018 - Springer
Mounting evidence suggests that diabetes mellitus (DM) is associated with mild cognitive
impairment (MCI), vascular dementia and Alzheimer's disease (AD). Biological, clinical and …
impairment (MCI), vascular dementia and Alzheimer's disease (AD). Biological, clinical and …
How does diabetes accelerate Alzheimer disease pathology?
C Sims-Robinson, B Kim, A Rosko… - Nature Reviews …, 2010 - nature.com
Diabetes and Alzheimer disease (AD)—two age-related diseases—are both increasing in
prevalence, and numerous studies have demonstrated that patients with diabetes have an …
prevalence, and numerous studies have demonstrated that patients with diabetes have an …
Therapy Insight: type 2 diabetes mellitus and the risk of late-onset Alzheimer's disease
MN Haan - Nature clinical practice Neurology, 2006 - nature.com
A number of well-designed epidemiological studies have linked type 2 diabetes mellitus
(T2DM) with an increased risk of Alzheimer's disease (AD). Several mechanisms could help …
(T2DM) with an increased risk of Alzheimer's disease (AD). Several mechanisms could help …
Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?
K Akter, EA Lanza, SA Martin… - British journal of …, 2011 - Wiley Online Library
Epidemiological and basic science evidence suggest a possible shared pathophysiology
between type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD). It has even been …
between type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD). It has even been …
Diabetes and dementia: Clinical perspective, innovation, knowledge gaps
MG Savelieff, KS Chen, SE Elzinga… - Journal of Diabetes and its …, 2022 - Elsevier
The world faces a pandemic-level prevalence of type 2 diabetes. In parallel with this
massive burden of metabolic disease is the growing prevalence of dementia as the …
massive burden of metabolic disease is the growing prevalence of dementia as the …
[HTML][HTML] Diabetes mellitus and dementia
T Ninomiya - Current diabetes reports, 2014 - Springer
Growing epidemiologic evidence has suggested that people with diabetes mellitus are at an
increased risk for the development of dementia. However, the results for the subtypes of …
increased risk for the development of dementia. However, the results for the subtypes of …
[HTML][HTML] Role of anti-diabetic drugs as therapeutic agents in Alzheimer's disease
Recent data have suggested a strong possible link between Type 2 Diabetes Mellitus and
Alzheimer's disease (AD), although exact mechanisms linking the two are still a matter of …
Alzheimer's disease (AD), although exact mechanisms linking the two are still a matter of …