Background The outcomes of exposure to neurotoxic chemicals early in life depend on the
properties of both the chemical and the host's environment. When our questions focus on the …

Developmental scientists have long been interested in how the environment influences
children's development. However, with few exceptions, they have not researched how …

Three proposals for enriching neurobehavioral toxicology studies are discussed. First, while
IQ has proven useful as a primary endpoint, such apical measures are limited: they obscure …

Background Environmental exposures play a critical role in the genesis of some child mental
health problems. Methods We open with a discussion of children's vulnerability to neurotoxic …

Background Studies of early-life neurotoxicant exposure have not been designed, analyzed,
or interpreted in the context of a fully developmental perspective. Objectives The goal of this …

Because the human population is biologically diverse and genetically heterogeneous, it is
not surprising that differences in susceptibility to disease among individuals with or without …

Principles and practices of pediatric neurotoxicology are reviewed here with the purpose of
guiding the design and execution of the planned National Children's Study. The developing …

A significant body of evidence supports the multifactorial etiology of neurodevelopmental
disorders (NDDs) affecting children. The present review focuses on early exposure to …

Vulnerable periods during the development of the nervous system are sensitive to
environmental insults because they are dependent on the temporal and regional emergence …

Purpose of review Early-life social and environmental exposures have independent effects
on many child health outcomes. Increasingly, investigators have suggested that these …