Monogenic atrial fibrillation as pathophysiological paradigms
Atrial fibrillation (AF) is the most common cardiac rhythm abnormality and represents a major
burden, both to patients and to health-care systems. In recent years, increasing evidence …
burden, both to patients and to health-care systems. In recent years, increasing evidence …
Atrial fibrillation genetics: is there a practical clinical value now or in the future?
WJ Hucker, H Saini, SA Lubitz, PT Ellinor - Canadian Journal of Cardiology, 2016 - Elsevier
Atrial fibrillation (AF) is the most common sustained arrhythmia and has significant clinical
impact. Over the last decade, our understanding of the genetics of AF has expanded …
impact. Over the last decade, our understanding of the genetics of AF has expanded …
[HTML][HTML] The genetic puzzle of familial atrial fibrillation
AAY Ragab, GDS Sitorus, BB Brundel… - Frontiers in …, 2020 - frontiersin.org
Atrial fibrillation (AF) is the most common clinical tachyarrhythmia. In Europe, AF is expected
to reach a prevalence of 18 million by 2060. This estimate will increase hospitalization for AF …
to reach a prevalence of 18 million by 2060. This estimate will increase hospitalization for AF …
[HTML][HTML] Genetics of atrial fibrillation: from families to genomes
IE Christophersen, PT Ellinor - Journal of human genetics, 2016 - nature.com
Atrial fibrillation (AF) is the most common cardiac rhythm disorder and the prevalence is
increasing. The disease confers an increased risk of severe complications such as heart …
increasing. The disease confers an increased risk of severe complications such as heart …
Emerging directions in the genetics of atrial fibrillation
NR Tucker, PT Ellinor - Circulation research, 2014 - Am Heart Assoc
Atrial fibrillation (AF) is the most common arrhythmia and is associated with increased
morbidity. As the population ages and the prevalence of AF continues to rise, the …
morbidity. As the population ages and the prevalence of AF continues to rise, the …
New advances in the genetic basis of atrial fibrillation
S Mahida, PT Ellinor - Journal of cardiovascular …, 2012 - Wiley Online Library
New Genetic Loci for Atrial Fibrillation. Over the past decade, compelling evidence has
emerged from population‐based studies to suggest that AF is a heritable disease. More …
emerged from population‐based studies to suggest that AF is a heritable disease. More …
Genomic basis of atrial fibrillation
A Bapat, CD Anderson, PT Ellinor, SA Lubitz - Heart, 2018 - heart.bmj.com
Atrial fibrillation (AF) is a prevalent arrhythmia associated with substantial morbidity,
mortality and costs. Available management strategies generally have limited efficacy and …
mortality and costs. Available management strategies generally have limited efficacy and …
Genetics of atrial fibrillation: implications for future research directions and personalized medicine
Atrial fibrillation (AF) was first described in humans approximately 100 years ago, 1 and
familial forms of AF were reported more than 70 years ago. 2, 3 Within the last 10 years, 3 …
familial forms of AF were reported more than 70 years ago. 2, 3 Within the last 10 years, 3 …
Genetics of atrial fibrillation: state of the art in 2017
Genetic variation is an important determinant of atrial fibrillation (AF) susceptibility.
Numerous rare variants in protein-coding sequences of genes have been associated with …
Numerous rare variants in protein-coding sequences of genes have been associated with …
Genetic aspects of atrial fibrillation
ACP Wiesfeld, MEW Hemels… - Cardiovascular …, 2005 - academic.oup.com
Atrial fibrillation (AF) occurs predominantly in the elderly and is commonly associated with
underlying cardiac diseases. A significant number of patients, however, have early onset AF …
underlying cardiac diseases. A significant number of patients, however, have early onset AF …