Extended phenotyping does not preclude the occurrence of delayed haemolytic transfusion reactions in sickle cell disease

J Gerritsma, V Bongaerts, C Eckhardt… - British Journal of …, 2022 - Wiley Online Library
Delayed haemolytic transfusion reaction (DHTR) is a potentially life‐threatening
complication of red blood cell (RBC) transfusions in sickle cell disease (SCD) and is …

Can we better predict delayed hemolytic transfusion reactions and hyperhemolysis in sickle cell disease?

BD Adkins, D Sharma, Q Eichbaum - Transfusion and Apheresis Science, 2020 - Elsevier
Delayed hemolytic transfusion reactions (DHTR) occurring in individuals with sickle cell
disease (SCD) are usually indolent but may rarely progress to life-threatening hemolysis …

Alloimmunization in patients with sickle cell disease and underrecognition of accompanying delayed hemolytic transfusion reactions

S Coleman, CM Westhoff, DF Friedman, ST Chou - Transfusion, 2019 - Wiley Online Library
BACKGROUND Patients with sickle cell disease (SCD) often require red blood cell (RBC)
transfusions but alloimmunization remains a significant complication. Alloantibodies can …

Challenges in the treatment and prevention of delayed hemolytic transfusion reactions with hyperhemolysis in sickle cell disease patients

CL Dean, CL Maier, S Chonat, A Chang… - …, 2019 - Wiley Online Library
BACKGROUND Delayed hemolytic transfusion reactions (DHTRs) are serious complications
of RBC transfusion that can occur in previously alloimmunized patients. Patients who require …

Clinical presentation of delayed hemolytic transfusion reactions and hyperhemolysis in sickle cell disease

RM Fasano, MJ Miller, S Chonat, SR Stowell - Transfusion Clinique et …, 2019 - Elsevier
Red blood cell (RBC) transfusion therapy is a key component in the comprehensive
management of patients with sickle cell disease (SCD). Consequently, most adult SCD …

Delayed haemolytic transfusion reaction in adults with sickle cell disease: a 5‐year experience

JB Vidler, K Gardner, K Amenyah… - British journal of …, 2015 - Wiley Online Library
Delayed haemolytic transfusion reactions (DHTR) are potentially life‐threatening
complications in patients with sickle cell disease (SCD). Between 1 August 2008 and 31 …

Management of delayed hemolytic transfusion reaction in sickle cell disease: prevention, diagnosis, treatment

F Pirenne, P Bartolucci, A Habibi - Transfusion Clinique et Biologique, 2017 - Elsevier
Transfusion remains a key treatment of sickle cell disease complications. However, delayed
hemolytic transfusion reaction, the most serious complication of transfusion, may be life …

How we treat delayed haemolytic transfusion reactions in patients with sickle cell disease

K Gardner, C Hoppe, A Mijovic… - British journal of …, 2015 - Wiley Online Library
Transfusion therapy is effective in the prevention and treatment of many complications of
sickle cell disease (SCD). However, its benefits must be balanced against its risks, including …

[HTML][HTML] Contribution of alternative complement pathway to delayed hemolytic transfusion reaction in sickle cell disease

S Chonat, MO Quarmyne, CM Bennett, CL Dean… - …, 2018 - ncbi.nlm.nih.gov
Transfusion of red blood cells (RBC) remains a primary treatment modality in patients with
sickle cell disease (SCD). Repeated exposure to alloantigens on transfused RBCs can lead …

The use of rituximab to prevent severe delayed haemolytic transfusion reaction in immunized patients with sickle cell disease

F Noizat‐Pirenne, A Habibi… - Vox …, 2015 - Wiley Online Library
Background Delayed haemolytic transfusion reaction (DHTR) is mainly caused by an
immune response to transfused red blood cells (RBC s). Immunized patients have a high …