Incubation of methamphetamine craving is associated with selective increases in expression of Bdnf and trkb, glutamate receptors, and epigenetic enzymes in cue …
Cue-induced methamphetamine seeking progressively increases after withdrawal
(incubation of methamphetamine craving), but the underlying mechanisms are largely …
(incubation of methamphetamine craving), but the underlying mechanisms are largely …
Role of dorsomedial striatum neuronal ensembles in incubation of methamphetamine craving after voluntary abstinence
D Caprioli, M Venniro, M Zhang… - Journal of …, 2017 - Soc Neuroscience
We recently developed a rat model of incubation of methamphetamine craving after choice-
based voluntary abstinence. Here, we studied the role of dorsolateral striatum (DLS) and …
based voluntary abstinence. Here, we studied the role of dorsolateral striatum (DLS) and …
Context-induced reinstatement of methamphetamine seeking is associated with unique molecular alterations in Fos-expressing dorsolateral striatum neurons
Context-induced reinstatement of drug seeking is a well established animal model for
assessing the neural mechanisms underlying context-induced drug relapse, a major factor …
assessing the neural mechanisms underlying context-induced drug relapse, a major factor …
Unique gene alterations are induced in FACS‐purified Fos‐positive neurons activated during cue‐induced relapse to heroin seeking
S Fanous, DH Guez‐Barber, EM Goldart… - Journal of …, 2013 - Wiley Online Library
Cue‐induced heroin seeking after prolonged withdrawal is associated with neuronal
activation and altered gene expression in prefrontal cortex (PFC). However, these previous …
activation and altered gene expression in prefrontal cortex (PFC). However, these previous …
Loss of plasticity in the D2-accumbens pallidal pathway promotes cocaine seeking
Distinct populations of D1-and D2-dopamine receptor-expressing medium spiny neurons
(D1-/D2-MSNs) comprise the nucleus accumbens, and activity in D1-MSNs promotes …
(D1-/D2-MSNs) comprise the nucleus accumbens, and activity in D1-MSNs promotes …
Cue reactivity in the ventral striatum characterizes heavy cannabis use, whereas reactivity in the dorsal striatum mediates dependent use
Background Animal models of addiction suggest that the transition from incentive-driven
drug use to habitual and ultimately compulsive drug use is mediated by a shift from ventral to …
drug use to habitual and ultimately compulsive drug use is mediated by a shift from ventral to …
Detection of molecular alterations in methamphetamine‐activated Fos‐expressing neurons from a single rat dorsal striatum using fluorescence‐activated cell sorting …
Methamphetamine and other drugs activate a small proportion of all neurons in the brain.
We previously developed a fluorescence‐activated cell sorting (FACS)‐based method to …
We previously developed a fluorescence‐activated cell sorting (FACS)‐based method to …
Prelimbic to accumbens core pathway is recruited in a dopamine-dependent manner to drive cued reinstatement of cocaine seeking
Glutamate inputs to nucleus accumbens (NAc) facilitate conditioned drug-seeking behavior
and primarily originate from medial prefrontal cortex (mPFC), basolateral amygdala (BLA) …
and primarily originate from medial prefrontal cortex (mPFC), basolateral amygdala (BLA) …
Incubation of cocaine-craving relates to glutamate over-flow within ventromedial prefrontal cortex
CB Shin, MM Serchia, JR Shahin, MA Ruppert-Majer… - …, 2016 - Elsevier
Craving elicited by drug-associated cues intensifies across protracted drug abstinence–a
phenomenon termed “incubation of craving”–and drug-craving in human addicts correlates …
phenomenon termed “incubation of craving”–and drug-craving in human addicts correlates …
Role of nucleus accumbens core but not shell in incubation of methamphetamine craving after voluntary abstinence
LM Rossi, I Reverte, D Ragozzino, A Badiani… - …, 2020 - nature.com
We recently introduced an animal model to study incubation of drug craving after prolonged
voluntary abstinence, mimicking the human condition of relapse after successful …
voluntary abstinence, mimicking the human condition of relapse after successful …