The multidrug resistance protein MRP1 functions as an ATP-dependent conjugate export
pump and confers multidrug resistance. We cloned MRP2 (symbol ABCC2), a MRP family …

The multidrug resistance proteins MRP2 (symbol ABCC2) and MRP3 (symbol ABCC3) are
conjugate export pumps expressed in hepatocytes. MRP2 is localized exclusively to the …

The membrane proteins mediating the ATP-dependent transport of lipophilic substances
conjugated to glutathione, glucuronate, or sulfate have been identified as members of the …

The multidrug resistance-associated protein Mrp2 is expressed in liver, kidney, and small
intestine and mediates ATP-dependent transport of conjugated organic anions across the …

The ATP-binding cassette transporter protein, multidrug resistance protein MRP1, was
purified from doxorubicin-selected H69AR lung tumor cells which express high levels of this …

Multidrug resistance protein 2 (MRP2) belongs to the ATP binding cassette family of
transporters. Its substrates include organic anions and anticancer drugs. We have used …

Human kidney proximal tubule epithelia express the ATP-dependent export pump for
anionic conjugates encoded by the MRP2 (cMRP/cMOAT) gene (symbol ABCC2). MRP2 …

The human multidrug resistance protein (MRP1) causes drug resistance by extruding drugs
from tumor cells. In addition to an MDR-like core, MRP1 contains an N-terminal membrane …

The human multidrug resistance protein MRP1 and its homolog, MRP2, are both suggested
as being involved in cancer drug resistance and the transport of organic anions. We …

The multidrug resistance (MDR) phenotype is associated with the overexpression of
members of the ATP-binding cassette family of proteins. These MDR transporters are …