The increasing bacterial drug resistance and the associated challenges in the treatment of
infections warrant the search for alternative therapeutic methods. Hope is placed in …

In vitro activity against methicillin-resistant Staphylococcus aureus (MRSA) and
Staphylococcus epidermidis biofilm producers from blood cultures of patients with prosthetic …

The antimicrobial peptide LL-37 belongs to the cathelicidin family and is one of the few
human bactericidal peptides with potent antistaphylococcal activity. Staphylococcus aureus …

To prevent biomaterial-associated infections, antibiotic agents are recommended for various
medical conditions requiring biomaterial implants, but resistance often appears after the …

Infection of bone is a severe complication due to the variety of bacteria causing it, their
resistance against classical antibiotics, the formation of a biofilm and the difficulty to …

We examined the benefits of short linear α-helical antimicrobial peptides (AMPs) invented in
our laboratory for treating bone infection and preventing microbial biofilm formation on …

Purpose. Antibiotic-loaded polymethylmethacrylate-based bone cement has been
implemented in orthopaedics to cope with implant-related infections associated with the …

Antibiotics resistant bacteria and biofilm formation on bone implants are the main challenges
of present treatment methods in hip or joint replacement surgeries. Recently, antimicrobial …

Polymethylmethacrylate (PMMA) bone cement mixed with antibiotics is used in orthopedic
surgery to cope with implant-related infections which are typically associated with the …

The biofilm-associated infections of bones are life-threatening diseases, requiring
application of dedicated antibiotics in order to counteract the tissue damage and spread of …