The treatment of invasive fungal infections remains challenging due to limitations in currently
available antifungal therapies including toxicity, interactions, restricted routes of …

Recent investigations have yielded both profound insights into the mechanisms required by
pathogenic fungi for virulence within the human host, as well as novel potential targets for …

In the late 1970s the options for systemic antifungal therapy doubled with the addition of
intravenous miconazole and oral ketoconazole to the two previously available agents …

In recent years, incidences of invasive fungal infections have greatly increased, especially in
immunosuppressed patients, but most today's antifungal drugs are not completely effective …

Invasive fungal diseases due to resistant yeasts and molds are an important and increasing
public health threat, likely due to a growing population of immunosuppressed hosts …

Invasive, life-threatening fungal infections are an important cause of morbidity and mortality,
particularly for patients with compromised immune function. The number of therapeutic …

In many ways, fungal diseases are forgotten or neglected. Given the significantly lower
frequency compared to similar bacterial etiologies across the spectrum of infectious …

Increasing incidence of fungal infections of recent times requires immediate intervention.
Fungal infections are seldom construed at initial stages that intensify the severity of …

The emergence of drug-resistant fungi poses a major threat to human health. Despite
advances in preventive, diagnostic, and therapeutic interventions, resistant fungal infections …

Fungi such as Fusarium spp., Curvularia spp., Alternaria spp. or Trichosporon beigelii, had
been thought to represent contamination or harmless colonization when isolated from …