Genetic analysis of heterogeneous subsets of circulating tumour cells from high grade serous ovarian carcinoma patients

DB Asante, GRKA Mohan, E Acheampong, M Ziman… - Scientific Reports, 2023 - nature.com
Circulating tumour cells (CTCs) are heterogenous and contain genetic information from the
tumour of origin. They bear specific intra-and extra-cellular protein markers aiding in their …

[HTML][HTML] Gene expression profiling of single circulating tumor cells in ovarian cancer–Establishment of a multi-marker gene panel

C Blassl, JD Kuhlmann, A Webers, P Wimberger… - Molecular …, 2016 - Elsevier
The presence of circulating tumor cells (CTCs) in the blood of ovarian cancer patients was
shown to correlate with decreased overall survival, whereby CTCs with epithelial …

Detection of abundant non-haematopoietic circulating cancer-related cells in patients with advanced epithelial ovarian cancer

J Kumar, D Chudasama, C Roberts, M Kubista… - Cells, 2019 - mdpi.com
Background: Current diagnosis and staging of advanced epithelial ovarian cancer (aEOC)
has important limitations and better biomarkers are needed. We investigate the performance …

Molecular characterization of circulating tumor cells in patients with ovarian cancer improves their prognostic significance—a study of the OVCAD consortium

E Obermayr, DC Castillo-Tong, D Pils, P Speiser… - Gynecologic …, 2013 - Elsevier
OBJECTIVE: The study aims at identifying novel markers for circulating tumor cells (CTCs) in
patients with epithelial ovarian cancer (EOC), and at evaluating their impact on outcome …

Complex tumor genomes inferred from single circulating tumor cells by array-CGH and next-generation sequencing

E Heitzer, M Auer, C Gasch, M Pichler, P Ulz… - Cancer research, 2013 - AACR
Circulating tumor cells (CTC) released into blood from primary cancers and metastases
reflect the current status of tumor genotypes, which are prone to changes. Here, we …

Profiling protein expression in circulating tumour cells using microfluidic western blotting

E Sinkala, E Sollier-Christen, C Renier… - Nature …, 2017 - nature.com
Circulating tumour cells (CTCs) are rare tumour cells found in the circulatory system of
certain cancer patients. The clinical and functional significance of CTCs is still under …

[HTML][HTML] Molecular characterization of circulating tumor cells in ovarian cancer

K Kolostova, M Pinkas, A Jakabova… - American journal of …, 2016 - ncbi.nlm.nih.gov
The main focus of the study was to detect circulating tumor cells (CTCs) in ovarian cancer
(OC) patients using a new methodological approach (MetaCell TM) which is based on size …

Dissecting molecular heterogeneity of circulating tumor cells (CTCs) from metastatic breast cancer patients through copy number aberration (CNA) and single …

T Rossi, D Angeli, M Tebaldi, P Fici, E Rossi, A Rocca… - Cancers, 2022 - mdpi.com
Simple Summary Circulating tumor cells (CTCs) are rare cells found in the bloodstream of
oncologic patients with a central role in the metastatic spread. In this study, we aim at …

Single-cell analysis of circulating tumor cells: how far have we come in the-omics era?

E Rossi, R Zamarchi - Frontiers in genetics, 2019 - frontiersin.org
Tumor cells detach from the primary tumor or metastatic sites and enter the peripheral blood,
often causing metastasis. These cells, named Circulating Tumor Cells (CTCs), display the …

Molecular characterization of circulating tumor cells—from bench to bedside

Y Li, S Wu, F Bai - Seminars in Cell & Developmental Biology, 2018 - Elsevier
Circulating tumor cells (CTCs) are cancer cells discovered in cancer patients' peripheral
blood that successfully escape from the primary tumor site and/or metastases, struggle to …