Immunocompetent human 3D organ-specific hormone-responding vaginal mucosa model of HIV-1 infection
I Saba, C Barat, S Chabaud, N Reyjon… - … Engineering Part C …, 2021 - liebertpub.com
The lack of appropriate experimental models often limits our ability to investigate the
establishment of infections in specific tissues. To reproduce the structural and spatial …
establishment of infections in specific tissues. To reproduce the structural and spatial …
Novel three-dimensional autologous tissue-engineered vaginal tissues using the self-assembly technique
Many diseases necessitate the substitution of vaginal tissues. Current replacement
therapies are associated with many complications. In this study, we aimed to create …
therapies are associated with many complications. In this study, we aimed to create …
HIV-1 infection in a small animal human vaginal xenograft model
TM Kish, MG Ward, PA Welsh… - JAIDS Journal of …, 2003 - journals.lww.com
A limitation in advancing the study of HIV-1 is the lack of a suitable small animal model
system that allows for HIV-1 infection to be monitored within human target epithelium …
system that allows for HIV-1 infection to be monitored within human target epithelium …
An ex vivo model of HIV-1 infection in human lymphoid tissue and cervico-vaginal tissue
A Introini, C Vanpouille, JC Grivel, L Margolis - Bio-protocol, 2014 - bio-protocol.org
Human tissue explants are a valuable tool to study the interactions between host and
infectious agents. They reliably mimic many important aspects of tissue cytoarchitecture and …
infectious agents. They reliably mimic many important aspects of tissue cytoarchitecture and …
Ex vivo HIV infection model of cervico-vaginal and rectal tissue
LA Ouattara, NC Vann, GF Doncel - HIV Reservoirs: Methods and …, 2022 - Springer
Globally, the most frequent route of HIV transmission is through sexual intercourse. In
women, sexual transmission of HIV involves cervical, vaginal, endometrial, and rectal …
women, sexual transmission of HIV involves cervical, vaginal, endometrial, and rectal …
Early events in HIV transmission through a human reconstructed vaginal mucosa
M Bouschbacher, M Bomsel, E Verronèse, S Gofflo… - Aids, 2008 - journals.lww.com
Objective: The early steps of HIV entry into intact vaginal mucosa still need to be clarified.
Here we investigated how HIV translocated across the vaginal pluristratified epithelium …
Here we investigated how HIV translocated across the vaginal pluristratified epithelium …
Cervico‐Vaginal Tissue Ex Vivo as a Model to Study Early Events in HIV‐1 Infection
M Merbah, A Introini, W Fitzgerald… - American Journal of …, 2011 - Wiley Online Library
Citation Merbah M, Introini A, Fitzgerald W, Grivel J‐C, Lisco A, Vanpouille C, Margolis L.
Cervico‐vaginal tissue ex vivo as a model to study early events in HIV‐1 infection. Am J …
Cervico‐vaginal tissue ex vivo as a model to study early events in HIV‐1 infection. Am J …
Ex vivo infection of human lymphoid tissue and female genital mucosa with human immunodeficiency virus 1 and histoculture
A Introini, C Vanpouille, W Fitzgerald… - JoVE (Journal of …, 2018 - jove.com
Histocultures allow studying intercellular interactions within human tissues, and they can be
employed to model host-pathogen interactions under controlled laboratory conditions. Ex …
employed to model host-pathogen interactions under controlled laboratory conditions. Ex …
3D human tissue models and microphysiological systems for HIV and related comorbidities
DE Yin, AC Palin, TB Lombo, RN Mahon, B Poon… - Trends in …, 2023 - cell.com
Abstract Three-dimensional (3D) human tissue models/microphysiological systems (eg,
organs-on-chips, organoids, and tissue explants) model HIV and related comorbidities and …
organs-on-chips, organoids, and tissue explants) model HIV and related comorbidities and …
[HTML][HTML] Protocol for in vitro establishment and long-term culture of mouse vaginal organoids
Healthy vaginal epithelium is essential for normal reproductive functions and protects
against infectious diseases. Here, we present a protocol for developing mouse vaginal …
against infectious diseases. Here, we present a protocol for developing mouse vaginal …