X-ray-Fluorescence Imaging for In Vivo Detection of Gold-Nanoparticle-Labeled Immune Cells: A GEANT4 Based Feasibility Study
A Ungerer, T Staufer, O Schmutzler, C Körnig… - Cancers, 2021 - mdpi.com
Simple Summary One novel approach in cancer therapy is the use of genetically modified
immune cells that are more specifically directed to a tumor than common chemotherapy …
immune cells that are more specifically directed to a tumor than common chemotherapy …
Feasibility of monitoring tumor response by tracking nanoparticle-labelled T cells using X-ray fluorescence imaging—A numerical study
H Kahl, T Staufer, C Körnig, O Schmutzler… - International Journal of …, 2021 - mdpi.com
Immunotherapy has been a breakthrough in cancer treatment, yet only a subgroup of
patients responds to these novel drugs. Parameters such as cytotoxic T-cell infiltration into …
patients responds to these novel drugs. Parameters such as cytotoxic T-cell infiltration into …
X-ray fluorescence uptake measurement of functionalized gold nanoparticles in tumor cell microsamples
O Schmutzler, S Graf, N Behm, WY Mansour… - International journal of …, 2021 - mdpi.com
Quantitative cellular in vitro nanoparticle uptake measurements are possible with a large
number of different techniques, however, all have their respective restrictions. Here, we …
number of different techniques, however, all have their respective restrictions. Here, we …
Quantitative imaging of gold nanoparticle distribution in a tumor-bearing mouse using benchtop x-ray fluorescence computed tomography
N Manohar, FJ Reynoso, P Diagaradjane, S Krishnan… - Scientific reports, 2016 - nature.com
X-ray fluorescence computed tomography (XFCT) is a technique that can identify, quantify
and locate elements within objects by detecting x-ray fluorescence (characteristic x-rays) …
and locate elements within objects by detecting x-ray fluorescence (characteristic x-rays) …
X-ray fluorescence computed tomography (XFCT) imaging of gold nanoparticle-loaded objects using 110 kVp x-rays
SK Cheong, BL Jones, AK Siddiqi, F Liu… - Physics in Medicine …, 2010 - iopscience.iop.org
A conventional x-ray fluorescence computed tomography (XFCT) technique requires
monochromatic synchrotron x-rays to simultaneously determine the spatial distribution and …
monochromatic synchrotron x-rays to simultaneously determine the spatial distribution and …
High-sensitivity imaging and quantification of intratumoral distributions of gold nanoparticles using a benchtop x-ray fluorescence imaging system
A high-sensitivity benchtop x-ray fluorescence (XRF) imaging system, based on a high-
power x-ray source and silicon drift detector, has been developed. This system allows gold L …
power x-ray source and silicon drift detector, has been developed. This system allows gold L …
Dynamic In Vivo X-ray Fluorescence Imaging of Gold in Living Mice Exposed to Gold Nanoparticles
Dynamic in vivo biodistribution of gold nanoparticles (GNPs) in living mice was first
successfully acquired by a pinhole X-ray fluorescence (XRF) imaging system using …
successfully acquired by a pinhole X-ray fluorescence (XRF) imaging system using …
Experimental demonstration of direct L‐shell x‐ray fluorescence imaging of gold nanoparticles using a benchtop x‐ray source
N Manohar, FJ Reynoso, SH Cho - Medical physics, 2013 - Wiley Online Library
Purpose: To develop a proof‐of‐principleL‐shell x‐ray fluorescence (XRF) imaging system
that locates and quantifies sparse concentrations of gold nanoparticles (GNPs) using a …
that locates and quantifies sparse concentrations of gold nanoparticles (GNPs) using a …
A bench-top K X-ray fluorescence system for quantitative measurement of gold nanoparticles for biological sample diagnostics
K Ricketts, C Guazzoni, A Castoldi, G Royle - Nuclear Instruments and …, 2016 - Elsevier
Gold nanoparticles can be targeted to biomarkers to give functional information on a range
of tumour characteristics. X-ray fluorescence (XRF) techniques offer potential quantitative …
of tumour characteristics. X-ray fluorescence (XRF) techniques offer potential quantitative …
Feasibility of x-ray fluorescence computed tomography (xfct) imaging of human lung tumors loaded with gold nanoparticles: A monte carlo study
MF Ahmed, S Jayarathna… - 2018 IEEE 12th …, 2018 - ieeexplore.ieee.org
We present a novel Monte Carlo model of x-ray fluorescence (XRF) computed tomography
(XFCT) imaging of human lung tumors loaded with gold nanoparticles (GNPs). In this model …
(XFCT) imaging of human lung tumors loaded with gold nanoparticles (GNPs). In this model …
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