Differential maturation of GIRK2-expressing neurons in the mouse cerebellum
C Aguado, L Fernández-Alacid, MJ Cabañero… - Journal of Chemical …, 2013 - Elsevier
The cerebellar cortex is among the brain regions showing the highest expression levels of G-
protein-gated inwardly-rectifying potassium (GIRK/Kir3) channels. Despite their critical …
protein-gated inwardly-rectifying potassium (GIRK/Kir3) channels. Despite their critical …
Cell type‐specific subunit composition of G protein‐gated potassium channels in the cerebellum
G protein‐gated inwardly rectifying potassium (GIRK/Kir3) channels regulate cellular
excitability and neurotransmission. In this study, we used biochemical and morphological …
excitability and neurotransmission. In this study, we used biochemical and morphological …
Developmental regulation of G protein‐gated inwardly‐rectifying K+ (GIRK/Kir3) channel subunits in the brain
L Fernández‐Alacid, M Watanabe… - European Journal of …, 2011 - Wiley Online Library
G protein‐gated inwardly‐rectifying K+ (GIRK/family 3 of inwardly‐rectifying K+) channels
are coupled to neurotransmitter action and can play important roles in modulating neuronal …
are coupled to neurotransmitter action and can play important roles in modulating neuronal …
GIRK1-mediated inwardly rectifying potassium current is a candidate mechanism behind Purkinje cell excitability, plasticity, and neuromodulation
P Lippiello, E Hoxha, F Tempia, MC Miniaci - The Cerebellum, 2020 - Springer
G-protein-coupled inwardly rectifying potassium (GIRK) channels contribute to the resting
membrane potential of many neurons and play an important role in controlling neuronal …
membrane potential of many neurons and play an important role in controlling neuronal …
GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior
E Marron Fernandez de Velasco, L Zhang, B N. Vo… - Scientific reports, 2017 - nature.com
Many neurotransmitters directly inhibit neurons by activating G protein-gated inwardly
rectifying K+ (GIRK) channels, thereby moderating the influence of excitatory input on …
rectifying K+ (GIRK) channels, thereby moderating the influence of excitatory input on …
Localization and targeting of GIRK channels in mammalian central neurons
G protein-gated inwardly rectifying K+(GIRK/K ir 3) channels are critical to brain function.
They hyperpolarize neurons in response to activation of different G protein-coupled …
They hyperpolarize neurons in response to activation of different G protein-coupled …
Distribution and neurochemical characterization of neurons expressing GIRK channels in the rat brain
LS Del Burgo, R Cortes, G Mengod… - Journal of …, 2008 - Wiley Online Library
G‐protein inwardly rectifying potassium (GIRK) channels mediate the synaptic actions of
numerous neurotransmitters in the mammalian brain and play an important role in the …
numerous neurotransmitters in the mammalian brain and play an important role in the …
[HTML][HTML] Abnormal expression of the GIRK2 potassium channel in hippocampus, frontal cortex and substantia nigra of Ts65Dn mouse: a model of Down syndrome
C Harashima, DM Jacobowitz, J Witta… - The Journal of …, 2006 - ncbi.nlm.nih.gov
Ts65Dn, a mouse model of Down syndrome (DS), demonstrates abnormal hippocampal
synaptic plasticity and behavioral abnormalities related to spatial learning and memory. The …
synaptic plasticity and behavioral abnormalities related to spatial learning and memory. The …
Abnormal expression of the G‐protein‐activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn …
C Harashima, DM Jacobowitz, J Witta… - Journal of …, 2006 - Wiley Online Library
Ts65Dn, a mouse model of Down syndrome (DS), demonstrates abnormal hippocampal
synaptic plasticity and behavioral abnormalities related to spatial learning and memory. The …
synaptic plasticity and behavioral abnormalities related to spatial learning and memory. The …
The expression and localisation of G-protein-coupled inwardly rectifying potassium (GIRK) channels is differentially altered in the hippocampus of two mouse models …
R Alfaro-Ruiz, A Martín-Belmonte, C Aguado… - International Journal of …, 2021 - mdpi.com
G protein-gated inwardly rectifying K+ (GIRK) channels are the main targets controlling
excitability and synaptic plasticity on hippocampal neurons. Consequently, dysfunction of …
excitability and synaptic plasticity on hippocampal neurons. Consequently, dysfunction of …