Methods of delivering agents to target cells including meth ods of immunotherapy, are
disclosed in Which monospeci? c binding proteins are administered to a host and bind to …

(57) ABSTRACT A method for intracellular delivery of drugs or other agents for diagnosis
and therapy of malignancies or immune mediated or inflammatory conditions. A targeting …

(63) Continuation of application No. 09/346.971, filed on Jul. 2,(List continued on next page.)
1999, now abandoned, which is a continuation of application No. 08/438,644, filed on May …

5,055,300 10/1991 0111116........... 424/409 W0 96/12475 5/1996 WIPO. 5,066,487 11/1991
Morelle et al. 424/68 W0 96/21464 7/1996 WIPO. 5,067,961 11/1991 K611116116161 …

This invention relates to the? eld of immune therapy of cancer, more speci? cally to
immunoconjugates of a cytotoxic moiety with a targeting moiety, more specifi cally to …

This application is a continuation-in-part of US applica tion Ser. No. 09/535,212, filed Mar.
27, 2000, now US Pat. No. 6,565,852, issued May 20, 2003, which is a continua tion-in-part …

Polymeric carriers are polypeptides comprising at least one drug-binding domain that non-
covalently binds a'drug. A polymeric carrier may be attached to an anti body speci? c for …

(57) ABSTRACT A new method is described for eliciting IgG antibody response to proteins
or synthetic peptides, particularly those that are weakly immunogenic, without the re …

an agent intended for use as a therapeutic, diagnostic, or in other applications is often highly
dependent on its ability to penetrate cellular membranes or tissues to access a target and/or …

Drug compositions formed as individual units, a multitude of which are employed as one or
more doses, to reduce or aleviate cancer in a living being by targeting to and destroying …