Active targeting microemulsion-based thermosensitive hydrogel against periodontitis by reconstructing Th17/Treg homeostasis via regulating ROS-macrophages …
J Li, M Li, C Zhang, Y Fei, Y Wang, Z Zhong… - International Journal of …, 2024 - Elsevier
Periodontitis is a multifactorial inflammatory disease characterized by severe alveolar bone
damage and attachment loss. The imbalance of T help 17 (Th17)/regulatory T cells (Treg) …
damage and attachment loss. The imbalance of T help 17 (Th17)/regulatory T cells (Treg) …
[HTML][HTML] Simultaneously boosting inflammation resolution and osteogenic differentiation in periodontitis using folic acid-modified liposome-thermosensitive hydrogel …
G Wang, C Peng, M Tang, Y Wang, J Li, H Chen… - Materials & Design, 2023 - Elsevier
Currently, the antibiotics-loaded hydrogels have not shown an over standard of clinical
effects on periodontitis treatment. Abnormal crosstalk between macrophages and …
effects on periodontitis treatment. Abnormal crosstalk between macrophages and …
[HTML][HTML] Ros-responsive and scavenging bifunctional hydrogel enables co-delivery of anti-inflammatory agent and osteogenetic nanoparticle for periodontitis …
C Peng, G Wang, J Li, Y Wang, Z Shu, M Tang, X Ma… - Materials & Design, 2024 - Elsevier
Periodontitis is characterized by local inflammatory response and the resultant alveolar
bone resorption. The elevated reactive oxygen species (ROS) level not only aggravates …
bone resorption. The elevated reactive oxygen species (ROS) level not only aggravates …
[HTML][HTML] Accelerating periodontal regeneration through injectable hydrogel-enabled sequential delivery of nanoceria and erythropoietin
Y Li, H Peng, W Tang, D Gu, S Ren, Y Yu, J Yang… - Materials & Design, 2023 - Elsevier
Periodontitis is a chronic inflammatory disease characterized by persistent host immune
overreaction, resulting in irregular alveolar shape after absorption, making local drug …
overreaction, resulting in irregular alveolar shape after absorption, making local drug …
[HTML][HTML] A five-in-one novel MOF-modified injectable hydrogel with thermo-sensitive and adhesive properties for promoting alveolar bone repair in periodontitis …
S Yang, Y Zhu, C Ji, H Zhu, A Lao, R Zhao, Y Hu… - Bioactive Materials, 2024 - Elsevier
Periodontitis is a chronic inflammatory disease caused by plaque that destroys the alveolar
bone tissues, resulting in tooth loss. Poor eradication of pathogenic microorganisms …
bone tissues, resulting in tooth loss. Poor eradication of pathogenic microorganisms …
Melatonin engineering M2 macrophage‐derived exosomes mediate endoplasmic reticulum stress and immune reprogramming for periodontitis therapy
Y Cui, S Hong, Y Xia, X Li, X He, X Hu, Y Li… - Advanced …, 2023 - Wiley Online Library
Periodontitis is a chronic infectious disease caused by bacterial irritation. As an essential
component of the host immunity, macrophages are highly plastic and play a crucial role in …
component of the host immunity, macrophages are highly plastic and play a crucial role in …
Injectable Nanocomposite Hydrogels with Strong Antibacterial, Osteoinductive, and ROS-Scavenging Capabilities for Periodontitis Treatment
Y Yu, Z You, X Li, F Lou, D Xiong, L Ye… - ACS Applied Materials …, 2024 - ACS Publications
Injectable antibacterial and osteoinductive hydrogels have received considerable attention
for promoting bone regeneration owing to their versatile functionalities. However, a current …
for promoting bone regeneration owing to their versatile functionalities. However, a current …
Quercetin-loaded mesoporous nano-delivery system remodels osteoimmune microenvironment to regenerate alveolar bone in periodontitis via the miR-21a-5p …
SY Yang, Y Hu, R Zhao, YN Zhou, Y Zhuang… - Journal of …, 2024 - Springer
Background Impaired osteo-/angiogenesis, excessive inflammation, and imbalance of the
osteoimmune homeostasis are involved in the pathogenesis of the alveolar bone defect …
osteoimmune homeostasis are involved in the pathogenesis of the alveolar bone defect …
[HTML][HTML] A Novel Lipopeptide–Functionalized Metal–Organic Framework for Periodontitis Therapy through the Htra1/FAK/YAP Pathway
X Wang, Q Wang, J Wang, X Wang, L Yin… - Biomaterials …, 2024 - spj.science.org
Periodontitis is a chronic inflammatory disease characterized by plaque accumulation,
resulting in immune microenvironment disorders and resorption of alveolar bone. To …
resulting in immune microenvironment disorders and resorption of alveolar bone. To …
Thermosensitive composite hydrogel with antibacterial, immunomodulatory, and osteogenic properties promotes periodontal bone regeneration via staged release of …
X Wang, Q Li, Z Liu, Y Wu, Z Zhang, J Mao… - Materials Today …, 2024 - Elsevier
Periodontitis is a common type of inflammatory bone loss induced by bacterial infection in
tooth-supporting tissue. Effective bone regeneration in the inflammatory microenvironment of …
tooth-supporting tissue. Effective bone regeneration in the inflammatory microenvironment of …