Recent data suggest that Pancreatic Neuroendocrine Tumours (PanNETs) originate from α-
or β-cells of the islets of Langerhans. The majority of PanNETs are non-functional and do not …

Pancreatic neuroendocrine tumors (PanNETs) are a common and deadly neoplasm of the
pancreas. Although the importance of genetic alterations in PanNETs has been known for …

Abstract Background Pancreatic neuroendocrine neoplasms (PanNENs) fall into two
subclasses: the well-differentiated, low-to high-grade pancreatic neuroendocrine tumors …

Neuroendocrine neoplasms (NENs) are a relatively rare group of heterogeneous tumours
originating from neuroendocrine cells found throughout the body. Pancreatic NENs …

Well-differentiated pancreatic neuroendocrine tumors (PanNETs) comprise∼ 1–3% of
pancreatic neoplasms. Although long considered as reasonably benign lesions, PanNETs …

Neuroendocrine tumours (NETs) may arise throughout the body and are a highly
heterogeneous, relatively rare class of neoplasms difficult to study also for the lack of …

Pancreatic cancer is one of the most common causes of cancer-related deaths worldwide.
The two major histological subtypes of pancreatic cancer are pancreatic ductal …

Here we report the DNA methylation profile of 84 sporadic pancreatic neuroendocrine
tumors (PanNETs) with associated clinical and genomic information. We identified three …

Pancreatic neuroendocrine neoplasms (PNENs) are biologically and clinically
heterogeneous. Here, we use a multi-omics approach to uncover the molecular factors …

The commonly mutated genes in pancreatic neuroendocrine tumors (PanNETs) are ATRX,
DAXX, and MEN1. We genotyped 64 PanNETs and found 58% carry ATRX, DAXX, and …