[HTML][HTML] Age-related changes in cardiac autonomic modulation and heart rate variability in mice

C Piantoni, L Carnevali, D Molla, A Barbuti… - Frontiers in …, 2021 - frontiersin.org
Objective The aim of this study was to assess age-related changes in cardiac autonomic
modulation and heart rate variability (HRV) and their association with spontaneous and …

Impacts of frailty on heart rate variability in aging mice: Roles of the autonomic nervous system and sinoatrial node

TW Dorey, HJ Jansen, M Moghtadaei, KL Jamieson… - Heart rhythm, 2021 - Elsevier
Background Heart rate variability (HRV) is determined by intrinsic sinoatrial node (SAN)
activity and the autonomic nervous system (ANS). HRV is reduced in aging; however, aging …

Rhythm dynamics of the aging heart: an experimental study using conscious, restrained mice

M Comelli, M Meo, DO Cervantes… - American Journal …, 2020 - journals.physiology.org
Heart rate variability (HRV) is a measure of variation in time interval between heartbeats and
reflects the influence of autonomic nervous system and circulating/locally released factors …

Acclimation to a thermoneutral environment abolishes age-associated alterations in heart rate and heart rate variability in conscious, unrestrained mice

JE Axsom, AP Nanavati, CA Rutishauser, JE Bonin… - Geroscience, 2020 - Springer
Mice are among the most widely used translational models of cardiovascular aging and offer
a method to quickly assess lifespan changes in a controlled environment. The standard …

[HTML][HTML] Heart rate variability reveals altered autonomic regulation in response to myocardial infarction in experimental animals

E Pizzo, S Berrettoni, R Kaul, DO Cervantes… - Frontiers in …, 2022 - frontiersin.org
The analysis of beating rate provides information on the modulatory action of the autonomic
nervous system on the heart, which mediates adjustments of cardiac function to meet …

Resting heart rate variability predicts vulnerability to pharmacologically-induced ventricular arrhythmias in male rats

L Carnevali, R Statello, A Sgoifo - Journal of Clinical Medicine, 2019 - mdpi.com
The electrical stability of the myocardium is dependent on the dynamic balance between
sympathetic and parasympathetic influences on the heart, which is reflected by heart rate …

Phenotypic screening for heart rate variability in the mouse

J Gehrmann, PE Hammer… - American Journal …, 2000 - journals.physiology.org
We developed a technology for heart rate (HR) variability (HRV) analysis in the mouse for
characterization of HR dynamics, modulated by vagal and sympathetic activity. The mouse is …

Sex differences in heart rate and heart rate variability in rats: implications for translational research

L Carnevali, M Barbetti, R Statello… - Frontiers in …, 2023 - frontiersin.org
The present study aimed to investigate sex differences in measures of cardiac chronotropy
and heart rate variability (HRV) in 132 young adult wild-type Groningen rats (n= 45 females) …

Temporal development of autonomic dysfunction in heart failure: effects of age in an ovine rapid-pacing model

MA Horn, EF Bode, SJ Borland… - … Series A: Biomedical …, 2016 - academic.oup.com
Heart failure (HF) is predominantly a disease of older adults and characterized by extensive
sympatho-vagal imbalance leading to impaired reflex control of heart rate (HR). However …

[HTML][HTML] Dissecting the roles of the autonomic nervous system and physical activity on circadian heart rate fluctuations in mice

N Barazi, N Polidovitch, R Debi, S Yakobov… - Frontiers in …, 2021 - frontiersin.org
Heart rate (HR) and blood pressure as well as adverse cardiovascular events show clear
circadian patterns, which are linked to interdependent daily variations in physical activity …