[图书][B] Identification and Evaluation of Synthetic Antimicrobial Peptide Variants Rationally Designed from the Bioactive Domain of AS-48 Bacteriocin Homologs
JN Ross - 2022 - search.proquest.com
Antibiotic resistance (ABR) is a naturally occurring phenomenon that is being exacerbated
by inappropriate use of antibiotics to treat human infections. Infections caused by resistant …
by inappropriate use of antibiotics to treat human infections. Infections caused by resistant …
Synthetic peptide libraries designed from a minimal alpha-helical domain of AS-48-Bacteriocin homologs exhibit potent antibacterial activity
JN Ross, FR Fields, VR Kalwajtys… - Frontiers in …, 2020 - frontiersin.org
The circularized bacteriocin enterocin AS-48 produced by Enterococcus sp. exhibits
antibacterial activity through membrane disruption. The membrane-penetrating activity of …
antibacterial activity through membrane disruption. The membrane-penetrating activity of …
Novel antimicrobial peptide discovery using machine learning and biophysical selection of minimal bacteriocin domains
FR Fields, SD Freed, KE Carothers… - Drug development …, 2020 - Wiley Online Library
Bacteriocins, the ribosomally produced antimicrobial peptides of bacteria, represent an
untapped source of promising antibiotic alternatives. However, bacteriocins display diverse …
untapped source of promising antibiotic alternatives. However, bacteriocins display diverse …
Expression in eukaryotic cells and purification of synthetic gene encoding enterocin P: a bacteriocin with broad antimicrobial spectrum
A Tanhaeian, MS Damavandi, D Mansury, K Ghaznini - amb express, 2019 - Springer
Due to the emergence of multidrug-resistant bacteria, treatment options for infectious
diseases are decreasing. Bacteriocins are small antimicrobial peptides produced by …
diseases are decreasing. Bacteriocins are small antimicrobial peptides produced by …
Rational design of syn-safencin, a novel linear antimicrobial peptide derived from the circular bacteriocin safencin AS-48
FR Fields, KE Carothers, RD Balsara… - The Journal of …, 2018 - nature.com
Bacteriocins hold unprecedented promise as a largely untapped source of antibiotic
alternatives in the age of multidrug resistance. Here, we describe the first approach to …
alternatives in the age of multidrug resistance. Here, we describe the first approach to …
Exploiting the Unique Biophysical Properties of Bacteriocins to Purify Bac1829 fromStaphylococcus aureusKSI1829
SS Crupper, JJ Iandolo - Protein expression and purification, 1997 - Elsevier
Bac1829 fromStaphylococcus aureusKSI1829 is a newly identified peptide bacteriocin that
inhibits a broad spectrum of bacteria. By taking advantage of its cationic and hydrophobic …
inhibits a broad spectrum of bacteria. By taking advantage of its cationic and hydrophobic …
Design, NMR characterization and activity of a 21‐residue peptide fragment of bacteriocin AS‐48 containing its putative membrane interacting region
MA Jiménez, AC Barrachi‐Saccilotto… - Journal of Peptide …, 2005 - Wiley Online Library
Abstract Bacteriocin AS‐48 is a 70‐residue cyclic polypeptide from Enterococcus faecalis
that shows a broad antimicrobial spectrum against both Gram‐positive and Gram‐negative …
that shows a broad antimicrobial spectrum against both Gram‐positive and Gram‐negative …
Effect of replacing glutamic residues upon the biological activity and stability of the circular enterocin AS-48
M Sanchez-Hidalgo, M Martínez-Bueno… - Journal of …, 2008 - academic.oup.com
Background Bacteriocins are antimicrobial peptides produced by bacteria and have a
relatively narrow range of activity against closely related strains. AS-48 is a circular …
relatively narrow range of activity against closely related strains. AS-48 is a circular …
Bacteriocins, potent antimicrobial peptides and the fight against multi drug resistant species: resistance is futile?
Despite highly specialized international interventions and policies in place today, the rapid
emergence and dissemination of resistant bacterial species continue to occur globally …
emergence and dissemination of resistant bacterial species continue to occur globally …
Natural antimicrobial peptides from bacteria: characteristics and potential applications to fight against antibiotic resistance
Because of the emergence of antibiotic‐resistant pathogens worldwide, a number of
infectious diseases have become difficult to treat. This threatening situation is worsened by …
infectious diseases have become difficult to treat. This threatening situation is worsened by …