Over the last 30 years, concomitant with successful transnational disease control programs
across Latin America, Chagas disease has expanded from a neglected, endemic parasitic …

Trypanosoma cruzi, the agent of Chagas disease (ChD), exhibits remarkable biological and
genetic diversity, along with eco-epidemiological complexity. In order to facilitate …

The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …

Chagas disease is an endemic zoonosis native to the Americas and is caused by the
kinetoplastid protozoan parasite Trypanosoma cruzi. The parasite is also highly genetically …

Chagas' disease is caused by the protozoan Trypanosoma cruzi and it has a variable
clinical outcome. The basis for this variability relies in part on the complexity of the parasite …

Background The genetic diversity of Trypanosoma cruzi, the etiological agent of Chagas
disease, has been traditionally divided in two major groups, T. cruzi I and II, corresponding …

The parasitic protozoan Trypanosoma cruzi, the causative agent of Chagas disease, is
widely distributed throughout the Americas, from the southern United States (US) to northern …

Chagas disease is an important vector-borne neglected tropical disease that causes great
health and economic losses. The etiological agent, Trypanosoma cruzi, is a protozoan …

The complexity of host–pathogen interactions often leads to distinct clinical outcomes upon
infection with different pathogen strains. In this Review, we explore the interactions between …

The protozoan Trypanosoma cruzi, its mammalian reservoirs, and vectors have existed in
nature for millions of years. The human infection, named Chagas disease, is a major public …