Reproduction, growth, stress, and metabolism are determined by endocrine/neuroendocrine
systems that regulate circulating hormone concentrations. All these systems generate …

Endocrine cells in the mammalian pituitary are arranged into three‐dimensional homotypic
networks that wire the gland and act to optimise hormone output by allowing the …

The secretion of peptide hormone by the pituitary gland is obligatory for controlling a wide-
range of downstream physiological processes. To achieve this, endocrine cells must …

Endocrine organs secrete a variety of hormones involved in the regulation of a multitude of
body functions. Although pancreatic islets were discovered at the turn of the 19th century …

Both endocrine and non-endocrine cells of the pituitary gland are organized into structural
and functional networks which are formed during embryonic development but which may be …

Recent advances in tridimensional (3D) tissue imaging have considerably enriched our view
of the pituitary gland and its development. Whereas traditional histology of the pituitary …

(3, 17-19, 21, 23, 29, 40, 42). Some of these effects may represent multiple sources and
hormone-growth factor activities in vivo that escaped detection by the classic approaches of …

Pituitary growth hormone (GH)-secreting cells regulate growth and metabolism in animals
and humans. To secrete highly ordered GH pulses (up to 1,000-fold rise in hormone levels …

The secretion of endocrine hormones from pituitary cells finely regulates a multitude of
homeostatic processes. To dynamically adapt to changing physiological status and …

Hormones are regulatory molecules that impact physiological functions. Much is known
about individual hormones, but general rules that connect the regulatory logic of different …