Bio-enhancement of Soy Isoflavones (Genistein & Daidzein) Using Bacillus coagulans in Letrozole Induced Polycystic Ovarian Syndrome by Regulating Endocrine …

J Bulsara, A Soni, P Patil, K Halpati, S Desai… - Probiotics and …, 2022 - Springer
Soy isoflavone (SIF), a natural phytoestrogen, is used in the condition of hormonal
imbalance. These isoflavones generally have low solubility resulting in low bioavailability …

Soy isoflavones exert beneficial effects on letrozole-induced rat polycystic ovary syndrome (PCOS) model through anti-androgenic mechanism

RK Rajan, B Balaji - Pharmaceutical biology, 2017 - Taylor & Francis
Context: Soy is the main source of phytoestrogens, which has long been used as traditional
food. One major subtype of phytoestrogens includes isoflavones and they are scientifically …

[HTML][HTML] Effects of soy isoflavones, resistant starch and antibiotics on polycystic ovary syndrome (PCOS)-like features in letrozole-treated rats

GSG Liyanage, R Inoue, M Fujitani, T Ishijima… - Nutrients, 2021 - mdpi.com
Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive-
aged women. Recently, various dietary interventions have been used extensively as a novel …

[HTML][HTML] Ficus deltoidea ameliorates biochemical, hormonal, and histomorphometric changes in letrozole-induced polycystic ovarian syndrome rats

MA Haslan, N Samsulrizal, N Hashim… - … Medicine and Therapies, 2021 - Springer
Background Insulin resistance and hormonal imbalances are key features in the
pathophysiology of polycystic ovarian syndrome (PCOS). We have previously shown that …

Soy isoflavones alleviate polycystic ovary syndrome in rats by regulating NF-κB signaling pathway

X Ma, X Li, LL Ma, Y Chen, S He - Bioengineered, 2021 - Taylor & Francis
Soy isoflavones have been widely used in the treatment of clinical gynecological diseases.
The aim of this study was to investigate the therapeutic effect and molecular mechanism of …

[HTML][HTML] Therapeutic exploration of polyherbal formulation against letrozole induced PCOS rats: a mechanistic approach

A Balasubramanian, S Pachiappan, S Mohan… - Heliyon, 2023 - cell.com
Objective This study aimed to develop an effective alternative medicine with multi potential
herbs against polycystic ovarian syndrome (PCOS) in rats induced by letrozole treatment …

Therapeutic effects of isoflavone-aglycone fraction from soybean (Glycine max L. Merrill) in rats with estradiol valerate-induced polycystic ovary syndrome as an …

SA Farkhad, H Khazali - Gynecological Endocrinology, 2019 - Taylor & Francis
Polycystic ovary syndrome (PCOS) is a proinflammatory/oxidative state resulting in
metabolic dysregulation and ovarian dysfunction. Isoflavones in soybean seed possess anti …

Effect of High‐Fat Diet on the Intestinal Flora in Letrozole‐Induced Polycystic Ovary Syndrome Rats

YH Zheng, Y Xu, HX Ma, CJ Liang… - … and Alternative Medicine, 2021 - Wiley Online Library
Aim. The aim of this study was to explore whether letrozole and high‐fat diets (HFD) can
induce obese insulin‐resistant polycystic ovary syndrome (PCOS) with intestinal flora …

[HTML][HTML] Effects of Bu Shen Hua Zhuo formula on the LPS/TLR4 pathway and gut microbiota in rats with letrozole-induced polycystic ovary syndrome

Y Wang, H Xiao, Y Liu, Q Tong, Y Yu, B Qi… - Frontiers in …, 2022 - frontiersin.org
Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in
gynecology. Traditional Chinese medicine (TCM) is widely used for the treatment of PCOS in …

Aqueous Ethanolic Extract of Inonotus obliquus Ameliorates Polycystic Ovarian Syndrome by Modulating Oxidative Stress and Downregulating TNF‐α and …

J Zhang, A Saeed, M Hussain… - Journal of Food …, 2024 - Wiley Online Library
Polycystic ovarian syndrome (PCOS) is a complex metabolic and endocrine disorder with
multifactorial etiology and complex pathogenesis. These intrinsic physiological changes …