Background With millions of victims worldwide, multiple sclerosis is the second most
common cause of disability among young adults. Although formidable advancements have …

Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the
central nervous system (CNS) affecting more than two million people worldwide. In MS …

Remyelination is a potent regenerative process in demyelinating diseases, such as multiple
sclerosis, the effective therapeutic promotion of which will fill an unmet clinical need. The …

Alzheimer's disease (AD) is the most common neurodegenerative disease and
oligodendrocyte degeneration and white matter damage play a critical role in the …

The role of fibroblast growth factor‐2 (FGF‐2) in multiple sclerosis and its animal model
experimental autoimmune encephalomyelitis is discussed. This study is the first to use FGF …

Fibroblast growth factors (FGFs) exert diverse biological effects by binding and activation of
specific fibroblast growth factor receptors (FGFRs). FGFs and FGFRs have been implicated …

Cognitive impairment is the core precursor to dementia and other cognitive disorders.
Current hypotheses suggest that they share a common pathological basis, such as …

Aims Fibroblast growth factor (FGF) signalling is dysregulated in multiple sclerosis (MS) and
other neurological and psychiatric conditions, but there is little or no consensus as to how …

Fibroblast growth factor (FGF) signaling contributes to failure of remyelination in multiple
sclerosis, but targeting this therapeutically is complicated by its functional pleiotropy. We …

Abstract Fibroblast growth factor 2 (FGF2) is an excellent candidate to regulate
remyelination based on its proposed actions in oligodendrocyte lineage cell development in …