The influence of skeletal muscle mitochondria and sex on critical torque and performance fatiguability in humans

RM McDougall, TR Tripp, BP Frankish… - The Journal of …, 2023 - Wiley Online Library
Critical torque (CT) represents the highest oxidative steady state for intermittent knee
extensor exercise, but the extent to which it is influenced by skeletal muscle mitochondria …

Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis

AK Meinild Lundby, RA Jacobs, S Gehrig… - Acta …, 2018 - Wiley Online Library
Aims (i) To determine whether exercise‐induced increases in muscle mitochondrial volume
density (MitoVD) are related to enlargement of existing mitochondria or de novo biogenesis …

Training-induced changes in mitochondrial content and respiratory function in human skeletal muscle

C Granata, NA Jamnick, DJ Bishop - Sports Medicine, 2018 - Springer
A sedentary lifestyle has been linked to a number of metabolic disorders that have been
associated with sub-optimal mitochondrial characteristics and an increased risk of …

Age‐related changes of skeletal muscle metabolic response to contraction are also sex‐dependent

MD Campbell, D Djukovic, D Raftery… - The Journal of …, 2023 - Wiley Online Library
Mitochondria adapt to increased energy demands during muscle contraction by acutely
altering metabolite fluxes and substrate oxidation. With age, an impaired mitochondrial …

The effects of exercise-induced muscle damage on critical torque

MK Szczyglowski, CJ Ade, JA Campbell… - European Journal of …, 2017 - Springer
Objective Exercise-induced muscle damage (EIMD) has been shown to reduce endurance
exercise performance. This study examined the effects of EIMD on critical torque (CT) and …

Markers of human skeletal muscle mitochondrial biogenesis and quality control: effects of age and aerobic exercise training

AR Konopka, MK Suer, CA Wolff… - Journals of Gerontology …, 2014 - academic.oup.com
Perturbations in mitochondrial health may foster age-related losses of aerobic capacity
(VO2peak) and skeletal muscle size. However, limited data exist regarding mitochondrial …

Effects of age and unaccustomed resistance exercise on mitochondrial transcript and protein abundance in skeletal muscle of men

DI Ogborn, BR McKay, JD Crane… - American Journal …, 2015 - journals.physiology.org
Mitochondrial dysfunction may contribute to age-associated muscle atrophy. Previous data
has shown that resistance exercise (RE) increases mitochondrial gene expression and …

The influence of age and aerobic fitness: effects on mitochondrial respiration in skeletal muscle

S Larsen, M Hey‐Mogensen, R Rabøl… - Acta …, 2012 - Wiley Online Library
Aim: Mitochondrial function has previously been studied in ageing, but never in humans
matched for maximal oxygen uptake (). Furthermore, the influence of ageing on …

A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

M Hey‐Mogensen, M Gram, MB Jensen… - The Journal of …, 2015 - Wiley Online Library
Key points The present study utilized a novel method aiming to investigate mitochondrial
function in human skeletal muscle at submaximal levels and at a predefined membrane …

[HTML][HTML] Mitochondrial respiratory chain function and content are preserved in the skeletal muscle of active very old men and women

RM Dodds, K Davies, A Granic, KG Hollingsworth… - Experimental …, 2018 - Elsevier
Introduction The loss of mitochondrial function and content have been implicated in
sarcopenia although they have been little studied in the very old, the group in which …