Cellular mechanotransduction, a critical regulator of numerous biological processes, is the
conversion from mechanical signals to biochemical signals regarding cell activities and …

All cells sense and integrate mechanical and biochemical cues from their environment to
orchestrate organismal development and maintain tissue homeostasis …

Mechanobiology is a rapidly growing research area focused on how mechanical forces and
properties influence biological systems at the cell, molecular, and tissue level, and how …

Living cells and tissues experience physical forces and chemical stimuli in the human body.
The process of converting mechanical forces into biochemical activities and gene …

Cells sense their physical surroundings through mechanotransduction—that is, by
translating mechanical forces and deformations into biochemical signals such as changes in …

Cells in tissues experience a plethora of forces that regulate their fate and modulate
development and homeostasis. Cells sense mechanical cues through localized …

Increasing evidence demonstrates that mechanical forces, in addition to soluble molecules,
impact cell and tissue functions in physiology and diseases. How living cells integrate …

The current focus of medicine on molecular genetics ignores the physical basis of disease
even though many of the problems that lead to pain and morbidity, and bring patients to the …

Living cells are constantly exposed to mechanical stimuli arising from the surrounding
extracellular matrix (ECM) or from neighboring cells. The intracellular molecular processes …

Mechanical cues are crucial for survival, adaptation, and normal homeostasis in virtually
every cell type. The transduction of mechanical messages into intracellular biochemical …