Background Androgens are required for both normal prostate development and prostate
carcinogenesis. We used DNA microarrays, representing approximately 18,000 genes, to …

The human prostate gland is an important target organ of androgenic hormones.
Testosterone and dihydrotestosterone interact with the androgen receptor to regulate vital …

Androgen-regulated genes (ARGs) are essential for the development of the prostate.
Ironically, ARGs are also responsible for the pathogenesis of prostate cancer. We used …

Background The development and maintenance of the prostate is dependent on androgens
and the androgen receptor. The androgen pathway continues to be important in prostate …

Androgens are critical regulators of prostate differentiation and function, as well as prostate
cancer growth and survival. Therefore, androgen ablation is the preferred systemic treatment …

Several methods have been developed for the comprehensive analysis of gene expression
in complex biological systems. Generally these procedures assess either a portion of the …

The androgen receptor (AR) plays a key role as a transcriptional factor in prostate
development and carcinogenesis. Identification of androgen-regulated genes is essential to …

Quantitative expression profile of androgen‐regulated genes (ARGs) was evaluated in the
hormone‐responsive prostate cancer cell line LNCaP by serial analysis of gene expression …

The androgen receptor (AR) mediates the growth-stimulatory effects of androgens in
prostate cancer cells. Identification of androgen-regulated genes in prostate cancer cells is …

Previously, we have developed a unique in vitro LNCaP cell model, which includes
androgen-dependent (LNCaP-C33), androgen-independent (LNCaP-C81) and an …