Exosomes: cell-derived nanoplatforms for the delivery of cancer therapeutics

H Kim, EH Kim, G Kwak, SG Chi, SH Kim… - International journal of …, 2020 - mdpi.com
Exosomes are cell-secreted nanovesicles that naturally contain biomolecular cargoes such
as lipids, proteins, and nucleic acids. Exosomes mediate intercellular communication …

Exosomes as a drug delivery system in cancer therapy: potential and challenges

G Kibria, EK Ramos, Y Wan, DR Gius… - Molecular …, 2018 - ACS Publications
Exosomes play a pivotal role in mediating intercellular communications and package
delivery. They have recently been discovered to serve as diagnostic biomarkers as well as a …

Exosome as a delivery vehicle for cancer therapy

B Moon, S Chang - Cells, 2022 - mdpi.com
Exosomes are small extracellular vesicles that are naturally produced and carry
biomolecules such as proteins, microRNAs, and metabolites. Because of their small size …

Engineering of exosomes to target cancer metastasis

Z Zhang, JA Dombroski, MR King - Cellular and Molecular Bioengineering, 2020 - Springer
As a nanoscale subset of extracellular vehicles, exosomes represent a new pathway of
intercellular communication by delivering cargos such as proteins and nucleic acids to …

Recent advances in exosome-based drug delivery for cancer therapy

H Kim, H Jang, H Cho, J Choi, KY Hwang, Y Choi… - Cancers, 2021 - mdpi.com
Simple Summary Exosomes derived from various sources can deliver therapeutic agents
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …

Exosome-like nanovectors for drug delivery in cancer

N Arrighetti, C Corbo, M Evangelopoulos… - Current medicinal …, 2019 - ingentaconnect.com
Cancer treatment still represents a formidable challenge, despite substantial advancements
in available therapies being made over the past decade. One major issue is poor …

Engineering exosomes for cancer therapy

KE Gilligan, RM Dwyer - International journal of molecular sciences, 2017 - mdpi.com
There remains an urgent need for novel therapeutic strategies to treat metastatic cancer,
which results in over 8 million deaths annually worldwide. Following secretion, exosomes …

[HTML][HTML] New advances in exosome-based targeted drug delivery systems

D Ferreira, JN Moreira, LR Rodrigues - Critical Reviews in Oncology …, 2022 - Elsevier
In recent years, various drug nano-delivery platforms have emerged to enhance drug
effectiveness in cancer treatment. However, their successful translation to clinics have been …

Exosomes, a new star for targeted delivery

H Chen, L Wang, X Zeng, H Schwarz… - Frontiers in cell and …, 2021 - frontiersin.org
Exosomes are cell-secreted nanoparticles (generally with a size of 30–150 nm) bearing
numerous biological molecules including nucleic acids, proteins and lipids, which are …

Exosomes as natural nanocarrier-based drug delivery system: recent insights and future perspectives

S Sen, J Xavier, N Kumar, MZ Ahmad, OP Ranjan - 3 Biotech, 2023 - Springer
Abstract Exosomes are nanosized (size~ 30–150 nm) natural vesicular structures released
from cells by physiological processes or pathological circumstances. Exosomes are growing …