Analytical Quality by design and greener solvent methods were applied to optimize the High-
Performance Liquid Chromatographic method for assessing atorvastatin calcium in bulk and …

The pharmaceutical industries rely heavily on liquid chromatographic methods for routine
quality control, which utilize hazardous solvents and have a direct impact on the …

The combined implementation of quality by design principles and green analytical chemistry
leads to development of green micellar HPLC method for analysis of atorvastatin calcium …

Clinical trials have demonstrated that combining fimasartan potassium trihydrate and
atorvastatin calcium produces better results for essential hypertension and dyslipidemia with …

In the present work, we investigated the development of a bioanalytical HPLC method of
rosuvastatin (RSV) calcium as per the Quality by Design (QbD)-based systematic …

The use of analytical quality by design (AQbD) approach in the optimization of the high‐
performance liquid chromatography (RP‐HPLC) method is a novel tool. Three factors and …

Abstract A Rapid Resolution Reversed Phase High-Performance Liquid Chromatography
(RR RP-HPLC) method has been developed and validated for the simultaneous …

Quantitative estimation of poorly water-soluble drugs involves use of organic solvents. Major
drawbacks of organic solvents include high cost, volatility and toxicity. In the present …

The current study explores a design and development of the simple, fast, green and
selective novel method of UPLC to quantify pitavastatin and ezetimibe simultaneously. The …

Background Response surface methodology by Box–Behnken design employing the
multivariate approach enables substantial improvement in the method development using …