Lymphatic pumping: mechanics, mechanisms and malfunction

JP Scallan, SD Zawieja… - The Journal of …, 2016 - Wiley Online Library
A combination of extrinsic (passive) and intrinsic (active) forces move lymph against a
hydrostatic pressure gradient in most regions of the body. The effectiveness of the lymph …

Lymphatic vessels and their surroundings: how local physical factors affect lymph flow

E Solari, C Marcozzi, D Negrini, A Moriondo - Biology, 2020 - mdpi.com
Simple Summary Lymphatic vessels are responsible for the drainage of liquids, solutes, and
cells from interstitial spaces and serosal cavities. Their task is fundamental in order to avoid …

Contractile physiology of lymphatics

DC Zawieja - Lymphatic research and biology, 2009 - liebertpub.com
The lymphatic system has important roles in body fluid regulation, macromolecular
homeostasis, lipid absorption, and immune function. To accomplish these roles, lymphatics …

Physiologic aspects of lymphatic contractile function: current perspectives

AA Gashev - Annals of the New York Academy of Sciences, 2002 - Wiley Online Library
The lymphatic system plays an important role in fluid/macromolecular balance, lipid
absorption, and immune functions, and is involved in many different pathologic conditions …

Hydrodynamic regulation of lymphatic transport and the impact of aging

AA Gashev, DC Zawieja - Pathophysiology, 2010 - Elsevier
To accomplish its normal roles in body fluid regulation/macromolecular homeostasis,
immune function, and lipid absorption; the lymphatic system must transport lymph from the …

Intrinsic pump-conduit behavior of lymphangions

CM Quick, AM Venugopal, AA Gashev… - American Journal …, 2007 - journals.physiology.org
Lymphangions, segments of lymphatic vessels bounded by valves, have characteristics of
both ventricles and arteries. They can act primarily like pumps when actively transporting …

Lymphatic smooth muscle: the motor unit of lymph drainage

PY von der Weid, DC Zawieja - The international journal of biochemistry & …, 2004 - Elsevier
Embedded into the wall of collecting lymphatic vessels and trunks, the lymphatic smooth
muscles are cardinal to the functions of the lymphatic system. Their intrinsic contractile …

Characterization of intact mesenteric lymphatic pump and its responsiveness to acute edemagenic stress

JN Benoit, DC Zawieja… - American Journal of …, 1989 - journals.physiology.org
The contractile properties of the mesenteric collecting lymphatics of the rat were analyzed
under control conditions and during periods of enhanced lymph formation using in vivo …

Contractility patterns of normal and pathologically changed human lymphatics

WL Olszewski - Annals of the new York Academy of Sciences, 2002 - Wiley Online Library
Human leg lymphatics contract spontaneously, rhythmically propelling lymph. This intrinsic
property regulates the fluid environment in the intercellular space in skin, connective tissue …

Regulatory mechanisms in lymphatic vessel contraction under normal and inflammatory conditions

PY von der Weid, M Muthuchamy - Pathophysiology, 2010 - Elsevier
The lymphatic system is composed of a dense network of lymphatic vessels, which are
critical components of physiological interstitial fluid transport. These vessels possess …