In this study, we developed a whole-cell biocatalysis process for high-level conversion of l-
lysine into 5-aminovalerate. To obtain the highly efficient whole-cell biocatalyst, five …

Microorganisms can utilize biomass to produce valuable chemicals, showing sustainable,
renewable and economic advantages compared with traditional chemical synthesis. As a …

Bioproduction of 5-aminovalerate (5AVA) from renewable feedstock can support a
sustainable biorefinery process to produce bioplastics, such as nylon 5 and nylon 56. In …

BACKGROUND Increasing environmental and energy concerns are pushing the
development of a bio‐based economy, employing highly reproducible, sustainable and …

Here, a new metabolic pathway for the production of 5-aminovalerate (5AVA) from l-lysine
via cadaverine as intermediate was established and this three-step-pathway comprises l …

Leucine dehydrogenase (LDH) is widely used in the preparation of L-2-aminobutyric acid (L-
2-ABA), however its wide application is limited by 2-ketobutyric acid (2-OBA) inhibition …

Aminovalerate is a potential C5 platform chemical for synthesis of valerolactam, 5-
hydroxyvalerate, glutarate and 1, 5-pentanediol. It is a metabolite of l-lysine catabolism …

In industry, L-alanine is biosynthesized using fermentation methods or catalyzed from L-
aspartic acid by aspartate β-decarboxylase (ASD). In this study, a triple-enzyme system was …

Glutarate is an important C5 platform chemical produced during the catabolism of L-lysine
through 5-aminovalerate (5-AMV) pathway. Here, we first established a whole-cell …

Abstract Cadaverine (also known as 1, 5-diaminopentane) is one of the most potential bio-
based products with a wide range of industrial applications. Bio-based polyamides …