The causes of evolvability and their evolution
Evolvability is the ability of a biological system to produce phenotypic variation that is both
heritable and adaptive. It has long been the subject of anecdotal observations and …
heritable and adaptive. It has long been the subject of anecdotal observations and …
Robustness and evolvability
J Masel, MV Trotter - Trends in Genetics, 2010 - cell.com
Why isn't random variation always deleterious? Are there factors that sometimes make
adaptation easier? Biological systems are extraordinarily robust to perturbation by …
adaptation easier? Biological systems are extraordinarily robust to perturbation by …
Evolution of evolvability in a developmental model
Evolvability, the ability of populations to adapt, can evolve through changes in the
mechanisms determining genetic variation and in the processes of development. Here we …
mechanisms determining genetic variation and in the processes of development. Here we …
The evolutionary dynamics of evolvability in a gene network model
Evolvability, the ability of populations to adapt, has recently emerged as a major unifying
concept in biology. Although the study of evolvability offers new insights into many important …
concept in biology. Although the study of evolvability offers new insights into many important …
Evolvability
M Kirschner, J Gerhart - Proceedings of the National …, 1998 - National Acad Sciences
Evolvability is an organism's capacity to generate heritable phenotypic variation. Metazoan
evolution is marked by great morphological and physiological diversification, although the …
evolution is marked by great morphological and physiological diversification, although the …
Is evolvability evolvable?
M Pigliucci - Nature Reviews Genetics, 2008 - nature.com
In recent years, biologists have increasingly been asking whether the ability to evolve—the
evolvability—of biological systems, itself evolves, and whether this phenomenon is the result …
evolvability—of biological systems, itself evolves, and whether this phenomenon is the result …
Robustness and evolvability: a paradox resolved
A Wagner - Proceedings of the Royal Society B …, 2008 - royalsocietypublishing.org
Understanding the relationship between robustness and evolvability is key to understand
how living things can withstand mutations, while producing ample variation that leads to …
how living things can withstand mutations, while producing ample variation that leads to …
Mutational robustness can facilitate adaptation
Robustness seems to be the opposite of evolvability. If phenotypes are robust against
mutation, we might expect that a population will have difficulty adapting to an environmental …
mutation, we might expect that a population will have difficulty adapting to an environmental …
Evolution of evolvability via adaptation of mutation rates
MA Bedau, NH Packard - Biosystems, 2003 - Elsevier
We examine a simple form of the evolution of evolvability—the evolution of mutation rates—
in a simple model system. The system is composed of many agents moving, reproducing …
in a simple model system. The system is composed of many agents moving, reproducing …
Adaptive evolution: evaluating empirical support for theoretical predictions
CF Olson-Manning, MR Wagner… - Nature Reviews …, 2012 - nature.com
Adaptive evolution is shaped by the interaction of population genetics, natural selection and
underlying network and biochemical constraints. Variation created by mutation, the raw …
underlying network and biochemical constraints. Variation created by mutation, the raw …