Development of a membrane and a bilayer of chitosan, gelatin, and polyhydroxybutyrate to be used as wound dressing for the regeneration of rat excisional wounds

JL Barbosa, MIA de Melo… - … Research Part A, 2024 - Wiley Online Library
The skin is the largest organ in the human body that acts as a protective barrier from the
outside environment. Certain dermatological pathologies or significant skin lesions can …

Adipose tissue‐derived mesenchymal stem cells and keratinocytes co‐culture on gelatin/chitosan/β‐glycerol phosphate nanoscaffold in skin regeneration

M Lotfi, H Naderi‐Meshkin, E Mahdipour… - Cell biology …, 2019 - Wiley Online Library
Using cell‐based engineered skin is an emerging strategy for treating difficult‐to‐heal
wounds. To date, much endeavor has been devoted to the fabrication of appropriate …

In Vivo Performance of Chitosan/Soy-Based Membranes as Wound-Dressing Devices for Acute Skin Wounds

TC Santos, B Höring, K Reise, AP Marques… - … Engineering Part A, 2013 - liebertpub.com
Wound management represents a major clinical challenge on what concerns healing
enhancement and pain control. The selection of an appropriate dressing plays an important …

Bioengineered skin substitutes: Advances and future trends

S Tavakoli, AS Klar - Applied Sciences, 2021 - mdpi.com
As the largest organ in the human body, the skin has the function of maintaining balance
and protecting from external factors such as bacteria, chemicals, and temperature. If the …

Chitosan scaffold co‐cultured with keratinocyte and fibroblast heals full thickness skin wounds in rabbit

D Revi, W Paul, TV Anilkumar… - Journal of Biomedical …, 2014 - Wiley Online Library
This study evaluated the modulatory effect of chitosan sponge co‐cultured with keratinocyte
and fibroblast on wound healing. Dermal fibroblasts and keratinocyte isolated from rabbit …

Hypoxia pretreatment of bone marrow—derived mesenchymal stem cells seeded in a collagen‐chitosan sponge scaffold promotes skin wound healing in diabetic rats …

C Tong, H Hao, L Xia, J Liu, D Ti, L Dong… - Wound Repair and …, 2016 - Wiley Online Library
Bone marrow—derived mesenchymal stem cells (BM‐MSCs) have properties that make
them promising for the treatment of chronic nonhealing wounds. The major challenge is …

A bilayer engineered skin substitute for wound repair in an irradiation-impeded healing model on rat

AB Mohd Hilmi, A Hassan, AS Halim - Advances in wound care, 2015 - liebertpub.com
Objective: An engineered skin substitute is produced to accelerate wound healing by
increasing the mechanical strength of the skin wound via high production of collagen …

Characterization of chitosan–gelatin scaffolds for dermal tissue engineering

HJ Tseng, TL Tsou, HJ Wang… - Journal of tissue …, 2013 - Wiley Online Library
Porous scaffolds for dermal tissue engineering were fabricated by freeze‐drying a mixture of
chitosan and gelatin (CG) solutions. Different crosslinking agents including glutaraldehyde …

Chitosan-Based Membranes for Skin Wound Repair in a Dorsal Fold Chamber Rat Model

MH Casimiro, LM Ferreira, PMP Santos, JP Leal… - Pharmaceutics, 2022 - mdpi.com
Frequently, deep partial and full-thickness skin wounds do not spontaneously regenerate.
To restore the normal function of skin, epidermal and dermal components have to be …

Gelatin/Carboxymethyl chitosan based scaffolds for dermal tissue engineering applications

T Agarwal, R Narayan, S Maji, S Behera… - International journal of …, 2016 - Elsevier
The present study delineates the preparation, characterization and application of gelatin-
carboxymethyl chitosan scaffolds for dermal tissue engineering. The effect of carboxymethyl …