A large body of experimental evidence suggests that neuroinflammation is a key
pathological event triggering and perpetuating the neurodegenerative process associated …

Despite advances in antimicrobial and anti-inflammatory therapies, inflammation and its
consequences still remain a significant problem in medicine. Acute inflammatory responses …

Lipopolysaccharide (LPS) is a cell-wall immunostimulatory endotoxin component of Gram-
negative bacteria. A growing body of evidence reveals that alterations in the bacterial …

Lipopolysaccharide (LPS), an endotoxin from Gram‐negative bacteria, acts as a potent
stimulator of microglia and has been used to study the inflammatory process in the …

Lipopolysaccharides (LPSs) are microbiome-derived glycolipids that are among the most
potent pro-inflammatory neurotoxins known. In Homo sapiens, the major sources of LPSs …

Research in the last two decades has unveiled an important role for neuroinflammation in
the degeneration of the nigrostriatal dopaminergic (DA) pathway that constitutes the …

Neuroinflammation is an important feature in the pathogenesis and progression of
neurodegenerative diseases such as Alzheimer´ s disease (AD), Parkinson´ s disease (PD) …

It has been suggested that brain inflammation is important in aggravation of brain damage
and/or that inflammation causes neurodegenerative diseases including Parkinson's disease …

In this study, we investigated lipopolysaccharide (LPS)-induced cognitive impairment and
neuroinflammation in C57BL/6J mice by using behavioral tests, immunofluorescence …

Background Systemic inflammation has been linked to synapse loss and cognitive decline in
human patients and animal models. A role for microglial release of pro-inflammatory …