Long non-coding RNA dysregulation is a frequent event in non-small cell lung carcinoma pathogenesis

A Acha-Sagredo, B Uko, P Pantazi, NG Bediaga… - British journal of …, 2020 - nature.com
Abstract Background Long non-coding RNAs compose an important level of epigenetic
regulation in normal physiology and disease. Despite the plethora of publications of …

[HTML][HTML] Identification and validation of long noncoding RNA biomarkers in human non–small-cell lung carcinomas

H Yu, Q Xu, F Liu, X Ye, J Wang, X Meng - Journal of thoracic oncology, 2015 - Elsevier
Introduction Dysregulation of long noncoding RNAs (lncRNAs) has been regarded as a
primary feature of several human cancers. However, the genome-wide expression and …

A potential signature of eight long non-coding RNAs predicts survival in patients with non-small cell lung cancer

M Zhou, M Guo, D He, X Wang, Y Cui, H Yang… - Journal of translational …, 2015 - Springer
Background Accumulated evidence suggests that dysregulated expression of long non-
coding RNAs (lncRNAs) may play a critical role in tumorigenesis and prognosis of cancer …

Long non-coding RNAs and their roles in non-small-cell lung cancer

MM Wei, GB Zhou - Genomics, Proteomics and Bioinformatics, 2016 - academic.oup.com
As a leading cause of cancer deaths worldwide, lung cancer is a collection of diseases with
diverse etiologies which can be broadly classified into small-cell lung cancer (SCLC) and …

Long noncoding RNAs: new insights into non-small cell lung cancer biology, diagnosis and therapy

B Ricciuti, C Mencaroni, L Paglialunga, F Paciullo… - Medical oncology, 2016 - Springer
Recent advances in tiling array and high throughput analyses revealed that at least 87.3% of
the human genome is actively transcribed, though< 3% of the human genome encodes …

[HTML][HTML] Long non-coding RNA as potential biomarkers in non-small-cell lung cancer: What do we know so far?

MA Osielska, PP Jagodziński - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Non-small-cell lung cancer (NSCLC) remains one of the most frequent types of lung cancer
characterized by its local advancement at diagnosis. Therefore, identification of new …

[HTML][HTML] Analysis of long non-coding RNA expression profiles in non-small cell lung cancer

L Wang, Z Chen, L An, Y Wang, Z Zhang… - Cellular physiology and …, 2016 - karger.com
Background/Aims: Long non-coding RNAs (lncRNAs) play an important role in
tumorigenesis. However, the role of lncRNA expression in human Non-small cell lung …

Long non‐coding RNA: a new paradigm for lung cancer

A Khandelwal, A Bacolla, KM Vasquez… - Molecular …, 2015 - Wiley Online Library
Lung cancer is the leading cause of cancer‐related deaths worldwide. Recent advances in
whole genome transcriptome analysis have enabled the identification of numerous …

Analysis of lncRNA expression profiles in non-small cell lung cancers (NSCLC) and their clinical subtypes

J Yang, J Lin, T Liu, T Chen, S Pan, W Huang, S Li - Lung cancer, 2014 - Elsevier
Lung cancer is one of the most common human cancers worldwide. Among all lung cancer
cases, non-small cell lung cancer (NSCLC) accounts for approximately 85%. Long non …

[HTML][HTML] Relapse-related long non-coding RNA signature to improve prognosis prediction of lung adenocarcinoma

M Zhou, W Xu, X Yue, H Zhao, Z Wang, H Shi… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Increasing evidence has highlighted the important roles of dysregulated long non-coding
RNA (lncRNA) expression in tumorigenesis, tumor progression and metastasis. However …