Measuring cfDNA integrity as a biomarker for predicting neoadjuvant chemotherapy response in breast cancer patients: a pilot study

C Giro, AMTD Yamada, FJSM Cruz… - Breast Cancer Research …, 2024 - Springer
Purpose Circulating cell-free DNA (cfDNA) is a promising biomarker for predicting treatment
response and disease outcomes in Breast Cancer (BC) patients undergoing neoadjuvant …

[HTML][HTML] Plasma cell-free DNA integrity: a potential biomarker to monitor the response of breast cancer to neoadjuvant chemotherapy

W Wang, W Zhang, L Su, J Sang… - Translational Cancer …, 2019 - ncbi.nlm.nih.gov
Background Although the clinical significance of neoadjuvant chemotherapy (NACT) is
widely recognized, there is still no effective means to monitor the therapeutic response in …

Identification of the plasma total cfDNA level before and after chemotherapy as an indicator of the neoadjuvant chemotherapy response in locally advanced breast …

G Ma, J Wang, H Huang, X Han, J Xu… - Cancer …, 2020 - Wiley Online Library
This study aimed to retrospectively evaluate the circulating free DNA (cfDNA) level in
patients with locally advanced breast cancer (LABC) having different neoadjuvant …

[HTML][HTML] Assessment of cell-free DNA (cfDNA) concentrations in the perioperative period can predict risk of recurrence in patients with non-metastatic breast cancer

F Hassan, JH Wang, C Cullinane, M Ita, M Corrigan… - Surgical oncology, 2022 - Elsevier
Background Circulating cell-free DNA (cfDNA) is a potential non-invasive biomarker of
disease status in patients with cancer, and provides important diagnostic and prognostic …

Cell-free DNA concentration as a biomarker of response and recurrence in HER2-negative breast cancer receiving neoadjuvant chemotherapy

MJM Magbanua, Z Ahmed, RW Sayaman… - Clinical Cancer …, 2024 - AACR
Purpose: We previously demonstrated the clinical significance of circulating tumor DNA
(ctDNA) in patients with HER2-negative breast cancer receiving neoadjuvant chemotherapy …

[HTML][HTML] Promoter profiles in plasma CfDNA exhibits a potential utility of predicting the efficacy of neoadjuvant chemotherapy in breast cancer patients

X Yang, Q Liu, Z Guo, X Yang, K Li, B Han… - Breast Cancer …, 2024 - Springer
Background Gene expression profiles in breast tissue biopsies contain information related to
chemotherapy efficacy. The promoter profiles in cell-free DNA (cfDNA) carrying gene …

[HTML][HTML] Efficacy of assessing circulating cell-free DNA using a simple fluorescence assay in patients with triple-negative breast cancer receiving neoadjuvant …

K Park, M Woo, JE Kim, JH Ahn, KH Jung, J Roh… - Oncotarget, 2018 - ncbi.nlm.nih.gov
This study aims to assess cell-free DNA (CFD) by a fluorescence assay as a biomarker for
early prediction of a pathologic complete response (pCR) and relapse in patients with triple …

[HTML][HTML] Circulating breast-derived DNA allows universal detection and monitoring of localized breast cancer

J Moss, A Zick, A Grinshpun, E Carmon, M Maoz… - Annals of …, 2020 - Elsevier
Background Tumor-derived circulating cell-free DNA (cfDNA) is present in the plasma of
individuals with cancer. Assays aimed at detecting common cancer mutations in cfDNA are …

[PDF][PDF] Association of perioperative cell-free DNA (cfDNA) concentrations with risk of recurrence in patients with breast cancer

F Hassan, JH Wang, C Cullinane, M Ita, M Corrigan… - 2021 - pdfs.semanticscholar.org
Background: Circulating cell-free DNA (cfDNA) is a potential biomarker of disease status in
cancer patients and provides valuable diagnostic and prognostic information in breast …

[HTML][HTML] Circulating tumor DNA in neoadjuvant-treated breast cancer reflects response and survival

MJM Magbanua, LB Swigart, HT Wu, GL Hirst, C Yau… - Annals of …, 2021 - Elsevier
Background Pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) is
strongly associated with favorable outcome. We examined the utility of serial circulating …