Background & Aims The limited availability of hepatitis Delta virus (HDV) infection models
has hindered studies of interactions between HDV and infected hepatocytes. The aim was to …

Hepatitis delta virus (HDV) requires hepatitis B virus (HBV) to complete its infection cycle
and causes severe hepatitis, with limited therapeutic options. To determine the prospect of T …

Background & Aims Chronic coinfection with HBV and HDV leads to the most aggressive
form of chronic viral hepatitis. Herein, we aimed to elucidate the molecular mechanisms …

Background & Aims Clinical studies have shown that hepatitis delta virus (HDV) infection
can persist for years and intrahepatic latency of the large delta antigen (HDAg) has been …

Liver disease associated to persistent infection with the hepatitis B virus (HBV) continues to
be a major health problem of global impact. Therapeutic regimens currently available can …

Chronic delta hepatitis, caused by hepatitis delta virus (HDV), is the most severe form of viral
hepatitis, affecting at least 20 million hepatitis B virus (HBV)–infected patients worldwide …

Co-infection with hepatitis B (HBV) and D virus (HDV) is associated with the most severe
course of liver disease. Interferon represents the only treatment currently approved …

Background & Aims Hepatitis B virus (HBV) and D virus (HDV) co-infections cause the most
severe form of viral hepatitis. HDV induces an innate immune response, but it is unknown …

Hepatitis delta is caused by infection with the hepatitis D virus (HDV) and is considered to be
the most severe form of viral hepatitis in humans. Hepatitis delta occurs only in hepatitis B …

Background & Aims Studying hepatitis delta virus (HDV) and developing new treatments is
hampered by the limited availability of small animal models. Herein, a description of a robust …