Metformin encapsulated gold nanoparticles (MTF‐GNPs): A promising antiglycation agent

F Alenazi, M Saleem, ASS Khaja… - Cell Biochemistry …, 2022 - Wiley Online Library
The generation of advanced glycation end products (AGEs) through nonenzymatic protein
glycation contributes to the pathogenesis of long‐lived diabetic problems. Metformin (MTF) …

Gold Nanoparticle‐Bioconjugated Aminoguanidine Inhibits Glycation Reaction: An In Vivo Study in a Diabetic Animal Model

S Ahmad, MS Khan, S Alouffi, S Khan… - BioMed Research …, 2021 - Wiley Online Library
Proteins undergo glycation resulting in the generation of advanced glycation end products
(AGEs) that play a central role in the onset and advancement of diabetes‐associated …

Inhibitory effect of gold nanoparticles on the D-ribose glycation of bovine serum albumin

W Liu, MA Cohenford, L Frost… - International journal …, 2014 - Taylor & Francis
Formation of advanced glycation end products (AGEs) by nonenzymatic glycation of proteins
is a major contributory factor to the pathophysiology of diabetic conditions including senile …

Antiglycating potential of gum arabic capped-silver nanoparticles

JM Ashraf, MA Ansari, I Choi, HM Khan… - Applied biochemistry …, 2014 - Springer
Advanced glycation end products are major contributors to the pathology of diabetes,
Alzheimer's disease, and atherosclerosis; accordingly, identification of antiglycation …

Suppression in advanced glycation adducts of human serum albumin by bio-enzymatically synthesized gold and silver nanoformulations: A potential tool to counteract …

F Ahmed, Q Husain - Biochimie, 2019 - Elsevier
Advanced glycation end-products (AGEs) from non-enzymatic glycation are implicated in
several degenerative diseases, including being a crucial contributor in secondary …

Gold nanosupplement in selective inhibition of methylglyoxal and key enzymes linked to diabetes

M Sengani, D Rajeswari - IET Nanobiotechnology, 2017 - Wiley Online Library
The non‐enzymatic glycation of macromolecules resulting into advanced glycation end
products (AGEs) that constituents lead secondary complication in diabetes. Currently …

[HTML][HTML] Green synthesis of silver nanoparticles and characterization of their inhibitory effects on AGEs formation using biophysical techniques

JM Ashraf, MA Ansari, HM Khan, MA Alzohairy… - Scientific reports, 2016 - nature.com
Advanced glycation end-products (AGEs) resulting from non-enzymatic glycation are one of
the major factors implicated in secondary complications of diabetes. Scientists are focusing …

Glycoxidation of biological macromolecules: a critical approach to halt the menace of glycation

S Ahmad, MS Khan, F Akhter, MS Khan, A Khan… - …, 2014 - academic.oup.com
Glycation is the result of covalent bonding of a free amino group of biological
macromolecules with a reducing sugar, which results in the formation of a Schiff base that …

[HTML][HTML] Evaluation of gallic acid-coated gold nanoparticles as an anti-aging ingredient

YZ Wu, YY Tsai, LS Chang, YJ Chen - Pharmaceuticals, 2021 - mdpi.com
Hyperglycemic environment-induced oxidative stress-mediated matrix metalloproteinase-1
(MMP-1) plays a crucial role in the degradation of the extracellular matrix (ECM), which …

Bioconjugation of gold nanoparticles with aminoguanidine as a potential inhibitor of non-enzymatic glycation reaction

Y Wang, H Wang, MS Khan, FM Husain… - Journal of …, 2021 - Taylor & Francis
The unavoidable glycation reaction is the major cause of diabetes and metabolic disorders.
The glycation reaction is enhanced in case when the glycating agent is reactive carbonyl …