Introduction Trends toward identifying risk factors of thrombotic complications had become
essential as an attempt to prevent and decrease the incidence of the complications …

The activated protein C (APC) resistance phenotype associated with an abnormal factor V
Leiden (FVL), and the G20210A prothrombin gene mutation are the most common findings …

The role of inherited thrombophilias in the pathogenesis of thrombosis, and their relation to
thromboembolic events and pregnancy complications, has escalated the demand for …

Thrombophilia is generally defined as an inherited disorder of the hemostatic system that
results in an increased risk of venous thromboembolism (VTE). There are several well …

In the past two decades, several mechanisms leading to thrombophilia have been
elucidated, and corresponding laboratory tests developed. At a time of financial constraints …

Abstract Background Mutations in the Factor V, Factor II and MTHFR genes are very high in
the MENA region and have not been linked widely to specific entities in the …

Laboratory testing for thrombophilia is complicated but essential for diagnosis. In 2017, the
cobas® Factor II and Factor V Test (cobas F2F5 test) was launched for use with the cobas z …

Background and aims To provide a fair estimate of the prevalence of factor V Leiden
(FVL)(G1691A), prothrombin (G20210A), and MTHFR (C677T) mutations in the Greek …

Venous thromboembolism (VTE) is a multifactorial disease that results from the interaction of
both inherited and acquired risk factors. The complications of these risk factors often lead to …

We have investigated the clinical usefulness of the activated protein C resistance
(APCR)/factor V Leiden mutation (FVL) test by sending out questionnaires to all Norwegian …