Progress in target drug molecules for Alzheimer's disease
J Xie, R Liang, Y Wang, J Huang… - Current Topics in …, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is a chronic neurodegenerative disease that 4 widespread in the
elderly. The etiology of AD is complicated, and its pathogenesis is still unclear. Although …
elderly. The etiology of AD is complicated, and its pathogenesis is still unclear. Although …
Recent developments in natural and synthetic drug research for Alzheimer's disease
Alzheimer's Disease (AD) is a progressive and degenerative neurological disorder
characterized by loss of cognition and memory. However, the pathogenesis of AD is still not …
characterized by loss of cognition and memory. However, the pathogenesis of AD is still not …
Current and emerging therapies for Alzheimer's disease
HB Nygaard - Clinical therapeutics, 2013 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative disorder, with a rapidly
increasing worldwide prevalence. Although no cure for AD has yet been found, substantial …
increasing worldwide prevalence. Although no cure for AD has yet been found, substantial …
[HTML][HTML] Small-molecule drugs development for Alzheimer's disease
W Yao, H Yang, J Yang - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Alzheimer's disease (AD) is an irreversible, progressive neurodegenerative brain disorder
with no effective therapeutic drugs currently. The complicated pathophysiology of AD is not …
with no effective therapeutic drugs currently. The complicated pathophysiology of AD is not …
Drugs for targeted therapies of Alzheimer's disease
C Tam, JH Wong, TB Ng, SKW Tsui… - Current medicinal …, 2019 - ingentaconnect.com
Alzheimer's disease (AD) is one type of neurodegenerative diseases, which is prevalent in
the elderly. Beta-amyloid (Aβ) plaques and phosphorylated tau-induced neurofibrillary …
the elderly. Beta-amyloid (Aβ) plaques and phosphorylated tau-induced neurofibrillary …
Emerging targets in neurodegeneration: new opportunities for Alzheimer's disease treatment?
A Rampa, S Gobbi, F Belluti… - Current Topics in Medicinal …, 2013 - ingentaconnect.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain
associated with memory impairment, progressive cognitive decline and changes in …
associated with memory impairment, progressive cognitive decline and changes in …
Therapeutic opportunities in Alzheimer disease: one for all or all for one?
MW Marlatt, KM Webber, PI Moreira… - Current medicinal …, 2005 - ingentaconnect.com
In recent years, Alzheimer disease (AD) has received great attention as an incurable and
fatal disease that threatens the lives of aging individuals. Debates regarding areas of …
fatal disease that threatens the lives of aging individuals. Debates regarding areas of …
Novel therapeutic strategies for dementia
R Cacabelos, C Torrellas, I Carrera… - CNS & Neurological …, 2016 - ingentaconnect.com
Dementia represents a major problem of health and disability, with a relevant economic
impact on our society. Despite important advances in pathogenesis, diagnosis and …
impact on our society. Despite important advances in pathogenesis, diagnosis and …
Designing multi-targeted therapeutics for the treatment of Alzheimer's disease
I Erdogan Orhan, F Sezer Senol - Current topics in medicinal …, 2016 - ingentaconnect.com
Due to multi-faceted pathology of AD; no drug can seize the progress of the disease,
whereas only the symptomatic treatment is available at the moment. Several drug classes to …
whereas only the symptomatic treatment is available at the moment. Several drug classes to …
New approaches to treating Alzheimer's disease
To date, no truly efficacious drugs for Alzheimer's disease (AD) have been developed;
moreover, all new anti-AD drugs developed since 2003 have failed. To succeed where …
moreover, all new anti-AD drugs developed since 2003 have failed. To succeed where …