A tutorial for pharmacogenomics implementation through end‐to‐end clinical decision support based on ten years of experience from PREDICT

M Liu, CL Vnencak‐Jones, BP Roland… - Clinical …, 2021 - Wiley Online Library
Vanderbilt University Medical Center implemented pharmacogenomics (PGx) testing with
the Pharmacogenomic Resource for Enhanced Decisions in Care and Treatment …

[HTML][HTML] Developing a prototype system for integrating pharmacogenomics findings into clinical practice

CL Overby, P Tarczy-Hornoch, IJ Kalet… - Journal of personalized …, 2012 - mdpi.com
Findings from pharmacogenomics (PGx) studies have the potential to be applied to
individualize drug therapy to improve efficacy and reduce adverse drug events. Researchers …

Pharmacogenomic clinical decision support: a scoping review

DM Smith, DT Wake… - Clinical Pharmacology & …, 2023 - Wiley Online Library
Clinical decision support (CDS) is often cited as an essential part of pharmacogenomics
(PGx) implementations. A multitude of strategies are available; however, it is unclear which …

Concepts driving pharmacogenomics implementation into everyday healthcare

J Giri, AM Moyer, SJ Bielinski… - Pharmacogenomics and …, 2019 - Taylor & Francis
Pharmacogenomics (PGx) is often promoted as the domain of precision medicine with the
greatest potential to readily impact everyday healthcare. Rapid advances in PGx knowledge …

Pharmacogenomic clinical decision support: a review, how‐to guide, and future vision

DT Wake, DM Smith, S Kazi… - Clinical Pharmacology …, 2022 - Wiley Online Library
Clinical decision support (CDS) is an essential part of any pharmacogenomics (PGx)
implementation. Increasingly, institutions have implemented CDS tools in the clinical setting …

[HTML][HTML] The Coriell personalized medicine collaborative pharmacogenomics appraisal, evidence scoring and interpretation system

N Gharani, MA Keller, CB Stack, LM Hodges… - Genome medicine, 2013 - Springer
Implementation of pharmacogenomics (PGx) in clinical care can lead to improved drug
efficacy and reduced adverse drug reactions. However, there has been a lag in adoption of …

The inclusion of health data standards in the implementation of pharmacogenomics systems: a scoping review

D Roosan, A Hwang, AV Law, J Chok… - …, 2020 - Taylor & Francis
Background: Despite potential benefits, the practice of incorporating pharmacogenomics
(PGx) results in clinical decisions has yet to diffuse widely. In this study, we conducted a …

[HTML][HTML] User considerations in assessing pharmacogenomic tests and their clinical support tools

G Mukerjee, A Huston, B Kabakchiev… - NPJ genomic …, 2018 - nature.com
Pharmacogenomic (PGx) testing is gaining recognition from physicians, pharmacists and
patients as a tool for evidence-based medication management. However, seemingly similar …

Prerequisites to implementing a pharmacogenomics program in a large health‐care system

KD Levy, BS Decker, JS Carpenter… - Clinical …, 2014 - Wiley Online Library
Pharmacogenomics (PGx) technology is advancing rapidly; however, clinical adoption is
lagging. The Indiana Institute of Personalized Medicine (IIPM) places a strong focus on …

[HTML][HTML] Sequence2Script: a web-based tool for translation of pharmacogenetic data into evidence-based prescribing recommendations

CA Bousman, P Wu, KJ Aitchison… - Frontiers in …, 2021 - frontiersin.org
Pharmacogenomic (PGx) testing has emerged as an effective strategy for informing drug
selection and dosing. This has led to an increase in the use of PGx testing in the clinic and …