Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines
Cancer vaccines based on resected tumors from patients have gained great interest as an
individualized cancer treatment strategy. However, eliciting a robust therapeutic effect with …
individualized cancer treatment strategy. However, eliciting a robust therapeutic effect with …
[HTML][HTML] Bacterial outer membrane vesicle-based cancer nanovaccines
X Gao, Q Feng, J Wang, X Zhao - Cancer Biology & Medicine, 2022 - ncbi.nlm.nih.gov
Tumor vaccines, a type of personalized tumor immunotherapy, have developed rapidly in
recent decades. These vaccines evoke tumor antigen-specific T cells to achieve immune …
recent decades. These vaccines evoke tumor antigen-specific T cells to achieve immune …
Nanovaccines integrating endogenous antigens and pathogenic adjuvants elicit potent antitumor immunity
Cancer nanovaccines have the ability to train the immune system to specifically recognize
and eliminate tumor cells. However, the vaccine's efficacy is hampered by limited access to …
and eliminate tumor cells. However, the vaccine's efficacy is hampered by limited access to …
[HTML][HTML] Cytomembrane nanovaccines show therapeutic effects by mimicking tumor cells and antigen presenting cells
Most cancer vaccines are unsuccessful in eliciting clinically relevant effects. Without using
exogenous antigens and adoptive cells, we show a concept of utilizing biologically …
exogenous antigens and adoptive cells, we show a concept of utilizing biologically …
Bifunctional fusion membrane‐based hydrogel enhances antitumor potency of autologous cancer vaccines by activating dendritic cells
Y Ke, J Zhu, Y Chu, L Cen, Y Fu, X Fan… - Advanced Functional …, 2022 - Wiley Online Library
Autologous tumor cell vaccine is an individualized tumor treatment strategy to elicit tumor‐
specific immune responses. However, it is difficult to exert efficacy in “cold” tumors, which …
specific immune responses. However, it is difficult to exert efficacy in “cold” tumors, which …
[HTML][HTML] Nanocarriers based on bacterial membrane materials for cancer vaccine delivery
Here we present a protocol for the construction and use of two types of nanocarrier based on
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …
bacterial membrane materials for cancer vaccine delivery. Cancer vaccines induce tumor …
[HTML][HTML] Engineered tumor cell-derived vaccines against cancer: The art of combating poison with poison
X Zhang, H Cui, W Zhang, Z Li, J Gao - Bioactive Materials, 2023 - Elsevier
Tumor vaccination is a promising approach for tumor immunotherapy because it presents
high specificity and few side effects. However, tumor vaccines that contain only a single …
high specificity and few side effects. However, tumor vaccines that contain only a single …
PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy
Despite the promise and advantages of autologous cancer cell vaccination, it remains
challenging to induce potent anti-tumor immune responses with traditional immunization …
challenging to induce potent anti-tumor immune responses with traditional immunization …
Development of an in situ cancer vaccine via combinational radiation and bacterial‐membrane‐coated nanoparticles
Neoantigens induced by random mutations and specific to an individual's cancer are the
most important tumor antigens recognized by T cells. Among immunologically “cold” tumors …
most important tumor antigens recognized by T cells. Among immunologically “cold” tumors …
Tumor associated macrophage and microbe: The potential targets of tumor vaccine delivery
J Jiang, J Mei, S Yi, C Feng, Y Ma, Y Liu, Y Liu… - Advanced drug delivery …, 2022 - Elsevier
The occurrence and development of tumors depend on the tumor microenvironment (TME),
which is made of various immune cells, activated fibroblasts, basement membrane …
which is made of various immune cells, activated fibroblasts, basement membrane …
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