The neurokinin 1 receptor (NK‐1R) is the main receptor for the tachykinin family of peptides.
Substance P (SP) is the major mammalian ligand and the one with the highest affinity. SP is …

The mammalian tachykinins (substance P, neurokinin A, and neurokinin B) are widely
distributed throughout the central and peripheral nervous systems, where they act as …

After its discovery in 1931, substance P (SP) remained the only mammalian member of the
family of tachykinin peptides for several decades. Tachykinins thus refer to peptides sharing …

The tachykinin NK1 receptor is widely distributed in both the central and peripheral nervous
system. In the CNS, NK1 receptors have been implicated in various behavioural responses …

The tachykinins, substance P, neurokinin A and neurokinin B, are a family of neuropeptides
widely distributed in the mammalian central and peripheral nervous system. In the …

The tachykinin NK1 receptor is widely expressed in the mammalian central and peripheral
nervous system. Powerful pharmacological tools (agonists and antagonists) are now …

In addition to the classical neurotransmitters, acetylcholine and noradrenaline, a wide
number of peptides with neurotransmitter activity have been identified in the past few years …

After binding to the specific neurokinin-1 (NK-1) receptor, the peptide substance P (SP),
which is widely distributed in both the central and peripheral nervous systems, induces …

The peptide substance P and its tachykinin receptor, neurokinin-1 (NK1), have been the
focus of considerable research for their role in a variety of both central and peripheral …

The neuropeptide substance P (SP) shows a widespread distribution in both the central and
peripheral nervous systems and it is known that after binding to the neurokinin-1 (NK-1) …