Bidirectional communication between oocytes and the companion granulosa cells is
essential for the development and functions of both compartments. Oocytes are deficient in …

Oocytes orchestrate the rate of follicular development and expression of genes in the
surrounding granulosa cells. Oocytes are deficient in their ability to carry out some metabolic …

Intercellular communication between oocytes and granulosa cells is essential for normal
follicular differentiation and oocyte development. Subtraction hybridization was used to …

Interaction between oocytes and granulosa cells is complex and involves both gap junctions
and paracrine signalling factors. Oocyte development in antral follicles is highly dependent …

A search for genes expressed more highly in mouse cumulus cells than mural granulosa
cells by subtraction hybridization yielded Slc38a3. SLC38A3 is a sodium-coupled neutral …

Evidence is now emerging that the oocyte plays a role in the development and function of
granulosa cells. This study focuses on the role of the oocyte in the proliferation of (1) …

Oocyte quality is a key limiting factor in female fertility, yet we have a poor understanding of
what constitutes oocyte quality or the mechanisms governing it. The ovarian follicular …

Cellular interactions in the mammalian ovarian follicle between its germ‐line and somatic
cell components are crucial for its development and function. These interactions are …

The development of follicles in the mammalian ovary involves a bidirectional communication
system between the follicular cells and oocyte that is now beginning to be characterized …

Recent studies have demonstrated a critical role for the oocyte in proliferation and
differentiation of granulosa cells and expansion of the cumulus oophorus in vitro. The …