Peripheral inflammatory biomarkers are associated with cognitive function and dementia: Framingham Heart Study Offspring cohort
Inflammatory protein biomarkers induced by immune responses have been associated with
cognitive decline and the pathogenesis of Alzheimer's disease (AD). Here, we investigate …
cognitive decline and the pathogenesis of Alzheimer's disease (AD). Here, we investigate …
[HTML][HTML] Association between inflammatory biomarkers and cognitive aging
Inflammatory cytokines and chemokines related to the innate and adaptive immune system
have been linked to neuroinflammation in Alzheimer's Disease, dementia, and cognitive …
have been linked to neuroinflammation in Alzheimer's Disease, dementia, and cognitive …
[HTML][HTML] Association of the inflammation-related proteome with dementia development at older age: results from a large, prospective, population-based cohort study
K Trares, M Bhardwaj, L Perna, H Stocker… - Alzheimer's Research & …, 2022 - Springer
Background Chronic inflammation is a central feature of several forms of dementia.
However, few details on the associations of blood-based inflammation-related proteins with …
However, few details on the associations of blood-based inflammation-related proteins with …
[HTML][HTML] Association between an inflammatory biomarker score and future dementia diagnosis in the population-based UK Biobank cohort of 500,000 people
K Mekli, A Lophatananon, A Maharani, JY Nazroo… - PloS one, 2023 - journals.plos.org
This study was designed to investigate the relationship between a systematic inflammatory
biomarker measure, concurrent and later cognitive performance, and future dementia risk …
biomarker measure, concurrent and later cognitive performance, and future dementia risk …
Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK‐ADRC cohort
KE Foley, Z Winder, TL Sudduth, BJ Martin… - Alzheimer's & …, 2024 - Wiley Online Library
INTRODUCTION Protein‐based plasma assays provide hope for improving accessibility and
specificity of molecular diagnostics to diagnose dementia. METHODS Plasma was obtained …
specificity of molecular diagnostics to diagnose dementia. METHODS Plasma was obtained …
Peripheral inflammatory biomarkers predict the deposition and progression of amyloid-β in cognitively unimpaired older adults
Introduction Systemic inflammation has been increasingly implicated in the pathogenesis of
Alzheimer's disease (AD), yet the mechanistic and temporal specificity of this relationship is …
Alzheimer's disease (AD), yet the mechanistic and temporal specificity of this relationship is …
[HTML][HTML] Associations of circulating C-reactive proteins, APOE ε4, and brain markers for Alzheimer's disease in healthy samples across the lifespan
The apolipoprotein E gene ε4 allele (APOE ε4) and higher circulating level of C-reactive
protein (CRP) have been extensively investigated as risk factors for Alzheimer's disease …
protein (CRP) have been extensively investigated as risk factors for Alzheimer's disease …
[HTML][HTML] Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype
Alzheimer disease (AD) is a chronic neurodegenerative disease with a multitude of
contributing genetic factors, many of which are related to inflammation. The apolipoprotein E …
contributing genetic factors, many of which are related to inflammation. The apolipoprotein E …
[HTML][HTML] Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain
Background The role of the innate immune system in Alzheimer's disease (AD) and
neurodegenerative disease susceptibility has recently been highlighted in genetic studies …
neurodegenerative disease susceptibility has recently been highlighted in genetic studies …
[HTML][HTML] Plasma proteins related to inflammatory diet predict future cognitive impairment
MR Duggan, L Butler, Z Peng, GN Daya… - Molecular …, 2023 - nature.com
Dysregulation of the immune system and dietary patterns that increase inflammation can
increase the risk for cognitive decline, but the mechanisms by which inflammatory nutritional …
increase the risk for cognitive decline, but the mechanisms by which inflammatory nutritional …