[HTML][HTML] 99mTc-labeled keratin gold-nanoparticles in a nephron-like microfluidic chip for photo-thermal therapy applications

V Frantellizzi, V Verrina, C Raso, M Pontico… - Materials Today …, 2022 - Elsevier
Biocompatible gold nanoparticles (AuNPs) are particularly interesting for photo-thermal
therapy (PTT) of cancer treatment because of their ability to convert light into heating …

Biomimetic keratin-coated gold nanoparticles for photo-thermal therapy in a 3D bioprinted glioblastoma tumor model

M Chirivì, C Bearzi, P Rosa, S Miglietta… - International Journal of …, 2022 - mdpi.com
Before entering human clinical studies to evaluate their safety and effectiveness, new drugs
and novel medical treatments are subject to extensive animal testing that are expensive and …

Biomimetic keratin gold nanoparticle-mediated in vitro photothermal therapy on glioblastoma multiforme

A Guglielmelli, P Rosa, M Contardi, M Prato… - …, 2020 - Future Medicine
Aim: To realize and characterize a new generation of keratin-coated gold nanoparticles (Ker-
AuNPs) as highly efficient photosensitive nanosized therapeutics for plasmonic …

Regenerated keratin-encapsulated gold nanorods for chemo-photothermal synergistic therapy

Z Du, K Yan, Y Cao, Y Li, Y Yao, G Yang - Materials Science and …, 2020 - Elsevier
Gold nanorods (AuNRs) have been widely applied to photothermal therapy against cancer.
However, the chemically synthesized AuNRs such as that via seed-mediate method usually …

Proteinticle/gold core/shell nanoparticles for targeted cancer therapy without nanotoxicity

KC Kwon, JH Ryu, JH Lee, EJ Lee, IC Kwon… - Advanced …, 2014 - Wiley Online Library
Although bulk gold is generally considered biocompatible and inert,[7] recent studies have
shown that gold NPs caused severe toxicity due to high-level accumulation in major organs …

Shape effects of gold nanoparticles in photothermal cancer therapy

W Yang, B Xia, L Wang, S Ma, H Liang, D Wang… - Materials Today …, 2021 - Elsevier
Abstract Gold Nanoparticles based Plasmonic Photothermal Therapy (PPTT) has recently
been extensively studied in cancer treatment, based on the local hyperthermia induced by …

Studies on effectiveness of PTT on 3D tumor model under microfluidic conditions using aptamer-modified nanoshells

D Kalinowska, I Grabowska-Jadach, M Liwinska… - Biosensors and …, 2019 - Elsevier
Herein, we present the research focused on the synthesis and application of aptamer-
modified gold nanoshells for photothermal therapy (PTT). NIR-absorbing hollow gold …

Fluorescent radiosensitizing gold nanoparticles

G Jiménez Sánchez, P Maury, L Stefancikova… - International Journal of …, 2019 - mdpi.com
Ultrasmall polyaminocarboxylate-coated gold nanoparticles (NPs), Au@ DTDTPA and Au@
TADOTAGA, that have been recently developed exhibit a promising potential for image …

Gold nanorod bioconjugates for active tumor targeting and photothermal therapy

HN Green, DV Martyshkin… - Journal of …, 2011 - Wiley Online Library
The mastery of active tumor targeting is a great challenge in near infrared photothermal
therapy (NIRPTT). To improve efficiency for targeted treatment of malignant tumors, we …

Gold hybrid nanoparticles for targeted phototherapy and cancer imaging

DK Kirui, DA Rey, CA Batt - Nanotechnology, 2010 - iopscience.iop.org
Gold and iron oxide hybrid nanoparticles (HNPs) synthesized by the thermal decomposition
technique are bio-functionalized with a single chain antibody, scFv, that binds to the A33 …