Intermuscular and intramuscular adipose tissues: Bad vs. good adipose tissues

GJ Hausman, U Basu, M Du, M Fernyhough-Culver… - Adipocyte, 2014 - Taylor & Francis
Human studies of the influence of aging and other factors on intermuscular fat (INTMF) were
reviewed. Intermuscular fat increased with weight loss, weight gain, or with no weight …

[HTML][HTML] A Key Gene, PLIN1, Can Affect Porcine Intramuscular Fat Content Based on Transcriptome Analysis

B Li, Q Weng, C Dong, Z Zhang, R Li, J Liu, A Jiang… - Genes, 2018 - mdpi.com
Intramuscular fat (IMF) content is an important indicator for meat quality evaluation.
However, the key genes and molecular regulatory mechanisms affecting IMF deposition …

Intermuscular adipose tissue in metabolic disease

BH Goodpaster, BC Bergman, AM Brennan… - Nature Reviews …, 2023 - nature.com
Intermuscular adipose tissue (IMAT) is a distinct adipose depot described in early reports as
a 'fatty replacement'or 'muscle fat infiltration'that was linked to ageing and neuromuscular …

Lipid metabolism and secretory function of porcine intramuscular adipocytes compared with subcutaneous and perirenal adipocytes

D Gardan, F Gondret, I Louveau - American Journal of …, 2006 - journals.physiology.org
The function of adipocytes interspersed between myofiber fasciculi in skeletal muscle
physiology and physiopathology is poorly documented. Because regional differences in …

Intermuscular fat: a review of the consequences and causes

O Addison, RL Marcus, PC LaStayo… - International journal of …, 2014 - Wiley Online Library
Muscle's structural composition is an important factor underlying muscle strength and
physical function in older adults. There is an increasing amount of research to support the …

Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity

M Bosma, LM Sparks, GJ Hooiveld… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Aims/hypothesis: While lipid deposition in the skeletal muscle is considered to be involved in
obesity-associated insulin resistance, neutral intramyocellular lipid (IMCL) accumulation per …

[HTML][HTML] Skeletal muscle size is a major predictor of intramuscular fat content regardless of age

H Akima, A Yoshiko, M Hioki, N Kanehira… - European Journal of …, 2015 - Springer
Purpose Skeletal muscles of older individuals have a larger amount of intramuscular
adipose tissue (IntraMAT) than those of younger individuals. It is not understood how aging …

The origin of intermuscular adipose tissue and its pathophysiological implications

R Vettor, G Milan, C Franzin, M Sanna… - American Journal …, 2009 - journals.physiology.org
The intermuscular adipose tissue (IMAT) is a depot of adipocytes located between muscle
bundles. Several investigations have recently been carried out to define the phenotype, the …

[HTML][HTML] Adipose tissue infiltration in skeletal muscle: age patterns and association with diabetes among men of African ancestry

I Miljkovic-Gacic, CL Gordon, BH Goodpaster… - The American journal of …, 2008 - Elsevier
Background Although obesity is strongly associated with diabetes, the greater prevalence of
diabetes in persons of African ancestry than in those of other ancestries cannot be explained …

Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance

IM Khan, XYD Perrard, G Brunner, H Lui… - International journal of …, 2015 - nature.com
Results: Macrophage and T-cell markers were upregulated in SM of obese compared with
lean humans. SM of obese mice had higher expression of inflammatory cytokines, with …